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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Aging Research

Browse the latest research summaries in the field of aging for spinal cord injury patients and caregivers.

Showing 61-70 of 150 results

Spinal Cord InjuryAgingPharmacology

Is Blood Loss Greater in Elderly Patients under Antiplatelet or Anticoagulant Medication for Cervical Spine Injury Surgery? A Japanese Multicenter Survey

Spine Surg Relat Res, 2022 • December 27, 2021

This multicenter study investigated whether antiplatelet/anticoagulant (APAC) drugs affect blood loss during surgery for cervical spine trauma in elderly patients. The study found no significant incre...

KEY FINDING: APAC use in elderly patients was not significantly associated with surgical blood loss according to the IPTW method with propensity scoring or linear mixed model analyses.

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AgingResearch Methodology & DesignPublic Health

Development and validation of a fall risk Questionnaire in Greek community-dwelling individuals over 60 years old

Journal of Frailty, Sarcopenia and Falls, 2022 • September 1, 2022

This study aimed to develop and validate a fall risk questionnaire (LRMS) for Greek community-dwelling individuals over 60 years old. The LRMS questionnaire is a self-reported, 11-item tool designed f...

KEY FINDING: The LRMS Questionnaire demonstrated high correlation with established fall risk assessment tools such as TUG, FES-I, and Tinetti Assessment Tool.

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Spinal Cord InjuryAgingTrauma

Differences in clinical characteristics of cervical spine injuries in older adults by external causes: a multicenter study of 1512 cases

Scientific Reports, 2022 • September 5, 2022

The study investigates cervical spine injuries in older adults, highlighting falls as the primary cause, particularly falls from ground level. Clinical characteristics and outcomes differ based on the...

KEY FINDING: Ground-level falls are the most common cause of cervical spine injuries in older adults.

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Spinal Cord InjuryAgingRehabilitation

Impact of Falls and Fear of Falling on Participation, Autonomy and Life Satisfaction in the First Year After Spinal Cord Injury

Frontiers in Rehabilitation Sciences, 2022 • June 9, 2022

This study examined the impact of falls and fear of falling on participation, autonomy, and life satisfaction in individuals with subacute SCI during the first year post-injury. The study found that f...

KEY FINDING: Over one third (38.3%) of participants fell over the 6-month tracking period.

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Spinal Cord InjuryParticipationAging

Global and domain-specific life satisfaction among older adults with long-term spinal cord injury

The Journal of Spinal Cord Medicine, 2021 • May 7, 2019

The study assessed global and domain-specific life satisfaction among older adults with long-term SCI and investigated associations with sociodemographics, injury characteristics, and secondary health...

KEY FINDING: Participants reported lower satisfaction with sexual life, activities of daily living, and somatic health.

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Spinal Cord InjuryAging

Clinical Associations with Telomere Length in Chronic Spinal Cord Injury

Spinal Cord, 2019 • December 1, 2019

This cross-sectional study examined the association between telomere length and clinical characteristics in individuals with chronic SCI, suggesting that more severe injuries may induce more substanti...

KEY FINDING: Telomere length was inversely related to age, confirming the expected association between aging and telomere shortening.

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AgingOrthopedicsRehabilitation

Does Blood Flow Restriction Therapy in Patients Older Than Age 50 Result in Muscle Hypertrophy, Increased Strength, or Greater Physical Function? A Systematic Review

Clin Orthop Relat Res, 2020 • December 18, 2019

This systematic review examined the effects of blood flow restriction (BFR) therapy on muscle hypertrophy, strength, and physical function in adults older than 50 years. The review found evidence sugg...

KEY FINDING: BFR, when combined with exercise, can lead to muscle hypertrophy as measured by various methods like muscle cross-sectional area and volume.

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Spinal Cord InjuryAgingMusculoskeletal Medicine

Contusion spinal cord injury upregulates p53 protein expression in rat soleus muscle at multiple timepoints but not key senescence cytokines

Physiological Reports, 2020 • January 1, 2020

The study investigated whether muscle disuse following spinal cord injury (SCI) induces cellular senescence and markers of senescence-associated secretory phenotypes (SASPs) in paralyzed skeletal musc...

KEY FINDING: SCI soleus muscle displayed 2- to 3-fold higher total p53 protein expression at 2 weeks, and at 1 and 2 months when compared with Sham.

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Spinal Cord InjuryAgingMedical Imaging

Can a relatively large spinal cord for the dural sac influence severity of paralysis in elderly patients with cervical spinal cord injury caused by minor trauma?

Medicine, 2020 • June 26, 2020

This study aimed to determine if a relatively large spinal cord for the dural sac influences the severity of paralysis in elderly patients with cervical spinal cord injury (SCI) caused by minor trauma...

KEY FINDING: A significant negative correlation was observed between the JOA score (indicating severity of paralysis) and the spinal cord/dural sac ratio at the mid-C5 vertebral level.

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Spinal Cord InjuryAgingPublic Health

In-Hospital Mortality for the Elderly with Acute Traumatic Spinal Cord Injury

JOURNAL OF NEUROTRAUMA, 2020 • November 1, 2020

This study analyzed data from 1340 elderly patients with tSCI to identify risk factors associated with in-hospital mortality in surgical and non-surgical patients. The study found that age, comorbidit...

KEY FINDING: In the surgical group, the odds of dying within 50 days post-surgery are six times higher for patients 77 years of age or older compared to those aged 65-76.

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