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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Latest Research Summaries

Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.

Showing 441-450 of 12,052 results

Spinal Cord InjuryRehabilitation

The trunk segmental motion complexity and balance performance in challenging seated perturbation among individuals with spinal cord injury

Journal of NeuroEngineering and Rehabilitation, 2025 • December 4, 2024

This study examined trunk segmental motion complexity in individuals with SCI during seated perturbations, assessing changes across six trunk segments and analyzing their influence on postural control...

KEY FINDING: Individuals with SCI showed significantly lower motion complexity in the lumbar and upper thoracic segments compared to healthy controls.

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Spinal Cord InjuryRegenerative MedicineGenetics

TET3‑facilitated differentiation of human umbilical cord mesenchymal stem cells into oligodendrocyte precursor cells for spinal cord injury recovery

Journal of Translational Medicine, 2024 • December 3, 2024

This study demonstrated that TET3-mediated demethylation reshapes the methylation patterns of HUCMSCs, enabling their efficient one-step conversion into OPCs and significantly reducing the time requir...

KEY FINDING: TET3 enhances HUCMSC differentiation into OPCs, evidenced by specific marker expression.

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Spinal Cord InjuryMedical ImagingOrthopedics

Impact of titanium mesh cage slotting width on anterior cervical corpectomy and fusion for compression cervical spondylosis with MRI T2WI hyperintensity: a one-year follow-up study

Journal of Orthopaedic Surgery and Research, 2024 • December 3, 2024

This study evaluated the impact of titanium mesh cage (TMC) slotting width on the outcomes of anterior cervical corpectomy and fusion (ACCF) in patients with spinal cord compression type cervical spon...

KEY FINDING: Patients in both groups showed significant postoperative improvement in NDI and JOA scores, indicating that ACCF is effective regardless of the slotting width.

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Spinal Cord InjuryNeurorehabilitationRehabilitation

On the role of visual feedback and physiotherapist‑patient interaction in robot‑assisted gait training: an eye‑tracking and HD‑EEG study

Journal of NeuroEngineering and Rehabilitation, 2024 • December 3, 2024

This study investigated the impact of visual feedback type and physiotherapist-patient interaction level on patient engagement during robot-assisted gait training (t-RAGT) using eye-tracking (ET) and ...

KEY FINDING: The type of visual feedback significantly affects all eye-tracking metrics across monitor, physiotherapist, and surrounding areas of interest.

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OncologyPharmacologyGenetics

The Cdk inhibitor dinaciclib as a promising anti-tumorigenic agent in biliary tract cancer

CANCER BIOLOGY & THERAPY, 2024 • December 3, 2024

This study investigates the efficacy of dinaciclib, a Cdk inhibitor, in treating biliary tract cancer (BTC) using in vitro models. The findings indicate that dinaciclib reduces cell viability, ATP lev...

KEY FINDING: Dinaciclib reduces cell viability, ATP levels, and proliferation rates in BTC cells.

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RehabilitationDisabilityPublic Health

The current physical activity in persons with disability in Qatar: a cross-sectional study

Front. Sports Act. Living, 2024 • December 3, 2024

This cross-sectional study assessed physical activity levels and sedentary behavior among persons with disabilities in Qatar. The study found that regular exercise had a positive impact on psychologic...

KEY FINDING: A majority of participants felt psychologically and emotionally better with regular physical activity.

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NeurologyBrain InjuryPublic Health

Mortality of chronic disorders of consciousness in adults and adolescents – a retrospective community based study from Salzburg, Austria

Frontiers in Neurology, 2024 • December 2, 2024

This community-based study provides epidemiological data on disorders of consciousness (DoC) in Salzburg, Austria, reporting an annual incidence of 2.2 cases per 100,000 inhabitants in the Salzburg No...

KEY FINDING: The crude 1- and 5-year mortality rates for DoC patients in Salzburg North were 25.9% and 55.1%, respectively.

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Spinal Cord InjuryRegenerative MedicineGenetics

Bone marrow mesenchymal stem cells modulate miR-202-3p to suppress neuronal apoptosis following spinal cord injury through autophagy activation via the AMPK, MAPK, and PI3K/AKT/mTOR signaling pathway

Scientific Reports, 2024 • December 2, 2024

This study investigates the role of bone marrow mesenchymal stem cells (BMMSCs) and miR-202-3p in treating spinal cord injury (SCI) in rats. The research demonstrates that BMMSCs, mediated by miR-202-...

KEY FINDING: BMMSCs improve motor function recovery in SCI rats, as evidenced by increased BBB scores and improved footprint analysis.

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SurgeryResearch Methodology & DesignMusculoskeletal Medicine

Cervical spinal cord injury following osteophyte excision for respiratory distress caused by diffuse idiopathic skeletal hyperostosis associated with ossification of posterior longitudinal ligament: a case report and literature review

BMC Musculoskeletal Disorders, 2024 • December 2, 2024

This case report details a 76-year-old male with DISH and OPLL who developed cervical spinal cord injury following osteophyte excision for respiratory distress and dysphagia. The patient's condition w...

KEY FINDING: Osteophyte excision in patients with cervical OPLL and spinal cord compression may lead to spinal cord injury due to increased intervertebral mobility.

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OncologyBioinformatics

Single-cell dissection of multifocal bladder cancer reveals malignant and immune cells variation between primary and recurrent tumor lesions

Communications Biology, 2024 • December 2, 2024

The study provides a single-cell level atlas characterizing the tumor microenvironment (TME) in primary and recurrent multifocal bladder cancer (BLCA). Analyses reveal significant differences in malig...

KEY FINDING: Malignant cells from recurrent multifocal bladder cancer exhibited higher interregional transcriptional similarity and consistent cellular communication.

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