Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 4,071-4,080 of 12,052 results
International Journal of Therapeutic Massage and Bodywork, 2022 • September 1, 2022
The paper characterizes a class of nonpathological spontaneous movements that occur in various contexts, including manual therapy, movement therapy, and spiritual practices. The authors aim to describ...
KEY FINDING: Spontaneous movements are seen as beneficial experiences with positive therapeutic effects. These characteristics are usually present, but individuals with spontaneous movements do not display all of these characteristics all of the time.
Journal of Neuroinflammation, 2022 • September 1, 2022
This study investigates the potential of human placental mesenchymal stem cell-derived small extracellular vesicles (hPMSCs-derived sEVs) to alleviate neuropathic pain in a spared nerve injury (SNI) m...
KEY FINDING: A single intrathecal injection of sEVs durably reversed mechanical hypersensitivity in the left hind paw of mice with partial sciatic nerve ligation.
Chinese Journal of Reparative and Reconstructive Surgery, 2022 • September 1, 2022
This study aimed to assess the efficacy of a modified orthopedic robot-assisted percutaneous kyphoplasty (PKP) for treating single-segment osteoporotic vertebral compression fractures (OVCF). The stud...
KEY FINDING: The robot group had a significantly shorter working channel establishment time compared to the C-arm group (P<0.001).
Frontiers in Neurology, 2022 • September 1, 2022
This study aimed to identify specific changes in brain gray matter volume (GMV) and white matter volume (WMV) following spinal cord injury (SCI) through a voxel-based meta-analysis of whole-brain voxe...
KEY FINDING: SCI patients showed significant gray matter volume (GMV) loss in the left insula and bilateral thalamus compared to healthy controls.
J Vet Intern Med, 2022 • September 1, 2022
The study validates a 50-step walking test as a pragmatic outcome measure for assessing ambulatory recovery in dogs after decompressive surgery for thoracolumbar disc herniation. The test effectively ...
KEY FINDING: The 50-step test effectively distinguished between outcomes for dogs with and without deep pain sensation, predicting recovery and expected recovery times.
Ann Transl Med, 2022 • September 1, 2022
Muscone has a protective effect on astrocytes in a MCD and inhibits astrocytes’ proliferation. Muscone is a significant biomarker for SCI treatment and does not have the side-effects of glucocorticoid...
KEY FINDING: Muscone reduced the levels of LDH, TNF-α, and MDA after injury, and upregulated the level of SOD.
Neurospine, 2022 • September 1, 2022
This review summarizes current research findings about the role of MSCs in improving complex pathology after SCI. MSCs exert a multimodal repair mechanism targeting multiple events in the secondary in...
KEY FINDING: MSCs can promote angiogenesis and vasculogenesis when transplanted into tissues, which is critical for tissue regeneration after SCI.
Neurospine, 2022 • September 1, 2022
Traumatic spinal cord injury (SCI) leads to secondary complications like chronic neuropathic pain (CNP) and spasticity, significantly affecting patients' daily lives. The mechanisms behind CNP post-SC...
KEY FINDING: Excitotoxicity mediated GABAergic cell loss, downregulation of glutamate acid decarboxylase enzyme, upregulation of gamma-aminobutyric acid (GABA) transporters, overactivation of glutamate receptors are some of the key evidence for hypoactive inhibitory tone contributing to CNP and spasticity post-SCI.
Neurospine, 2022 • September 1, 2022
This study aimed to identify factors affecting the prognosis of syringomyelia in CM-I patients after decompression surgery, focusing on the morphometric characteristics of the syrinx. The study found ...
KEY FINDING: Timely decompression surgery leads to better outcomes in CM-I patients with syringomyelia, reflected in higher CCOS scores and syrinx resolution rates.
Neurospine, 2022 • September 1, 2022
This meta-analysis assessed the impact of therapeutic hypothermia on patients with acute SCI, finding that hypothermia led to neurological improvement in over half of the patients. Systemic hypothermi...
KEY FINDING: Hypothermia in acute SCI improved neurological function in 55.8% of patients.