Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 3,961-3,970 of 12,052 results
Neuropsychopharmacology, 2022 • September 30, 2022
This article is a correction to a previously published study concerning the association of GFAP concentration and posttraumatic stress disorder in patients with mild traumatic brain injury. The correc...
KEY FINDING: The primary finding is a correction of the material measured; GFAP was measured in plasma, not serum, in the original study.
Cells, 2022 • September 30, 2022
This review examines the potential of activity-based interventions (ABI) to alleviate neuropathic pain (NP) following spinal cord injury (SCI) in preclinical rodent models. It focuses on molecular and...
KEY FINDING: Weight-bearing rhythmic activity-based paradigms seem effective for neuropathic pain relief after spinal cord injury, regardless of whether interventions are started early or delayed, or applied for short or long durations, but the benefits may not persist long after halting the interventions.
Spinal Cord Series and Cases, 2022 • September 30, 2022
This case report describes a rare instance of spinal cord compression caused by a spinal cord stimulator (SCS) electrode array in a 58-year-old woman with a history of back pain and multiple spine sur...
KEY FINDING: The case report highlights a very rare complication of SCS, spinal cord compression due to the electrode array.
Mediators of Inflammation, 2022 • September 30, 2022
The study investigates the effects of LPA on spinal cord neurons, particularly concerning cytotoxicity, apoptosis, DNA damage, and oxidative stress, using an in vitro model. It finds that LPA (18:1) n...
KEY FINDING: LPA (18:1) treatment decreases cell viability and increases LDH release in spinal cord neurons, indicating cytotoxicity.
Computational and Mathematical Methods in Medicine, 2022 • September 29, 2022
This study compared anterior cervical corpectomy and fusion with posterior total laminectomy for treating cervical spinal cord injury. The anterior approach showed benefits in perioperative indicators...
KEY FINDING: The amount of blood loss, wound diameters, operation times, and operation costs were higher in the posterior approach group compared to the anterior approach group.
Brain Sci., 2022 • September 29, 2022
This study investigates the pro-angiogenesis of M2 macrophage-derived exosomes on SCI. The findings reveal that M2 macrophage exosomes improve neurological functional recovery and angiogenesis post-SC...
KEY FINDING: M2 macrophage exosomes alleviate tissue damage and enhance functional recovery post-SCI in rats.
Int. J. Mol. Sci., 2022 • September 29, 2022
This work introduces a cost-efficient gelatin-based submicron patterned hydrogel–fiber composite with tuned stiffness, able to support cell attachment, differentiation and alignment of neurons derived f...
KEY FINDING: Fiber–hydrogel composites with a modulus of about 20 kPa showed the strongest cell attachment and highest cell proliferation, rendering them an ideal differentiation support.
Sensors, 2022 • September 29, 2022
This study developed and validated a methodology for classifying wheelchair-related shoulder-loading activities (SL-ADL) using wearable sensor data and deep learning. A deep learning model, incorporat...
KEY FINDING: The trained deep learning algorithm achieved an overall accuracy of 98% in classifying wheelchair-related shoulder-loading activities (SL-ADL).
Toxins, 2022 • September 29, 2022
This retrospective study analyzed the reasons for discontinuation of Botulinum Toxin A (BoNT-A) treatment in 56 patients with spasticity due to stroke, multiple sclerosis, spinal cord injury, or traum...
KEY FINDING: Logistic reasons (including distance problems and difficulty in being accompanied) were the most common reason reported for treatment discontinuation (21, [37.5%]), especially in stroke patients
Int. J. Mol. Sci., 2022 • September 29, 2022
This study examined the temporal profile of circulating white blood cells during the progression of DCM in a mouse model. The research aimed to identify potential systemic hematological changes that c...
KEY FINDING: Circulating monocytes increased four-fold at 3 weeks following DCM induction, but these differences normalized at subsequent time points.