Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 3,861-3,870 of 12,052 results
PLOS ONE, 2022 • October 18, 2022
This study evaluated the efficacy of topical oclacitinib, in conjunction with nail trimming, for treating murine ulcerative dermatitis (UD) compared to nail trimming alone or nail trimming combined wi...
KEY FINDING: Mean UD scores decreased from day 1 to day 7 and from day 1 to day 14 for all treatment groups, indicating improvement in skin lesions regardless of the treatment.
Korean J Neurotrauma, 2022 • October 18, 2022
This case report describes a patient who developed posterior cord syndrome, characterized by decreased proprioception, immediately after spinal cord stimulation (SCS) electrode lead insertion for chro...
KEY FINDING: The patient developed posterior cord syndrome, specifically a loss of proprioception, immediately after the insertion of a paddle-type SCS electrode lead.
J Neural Eng., 2022 • October 18, 2022
This study introduces a machine-learning framework to identify EES parameters capable of generating desired patterns of EMG activity. The approach involves training a forward neural network model to p...
KEY FINDING: Neural networks can effectively approximate the complex computations of the spinal cord related to sensorimotor control, accurately predicting muscle activity based on EES parameters.
J Rehabil Med, 2022 • October 18, 2022
This study provides an evidence base regarding the lived experience of persons with SCI in south-eastern Brazil. The results suggest that there is a need for interventions and public policies designed...
KEY FINDING: Most people with spinal cord injury in south-eastern Brazil are male and paraplegic, health problems and spasticity is considered their most problematic health condition.
Cureus, 2022 • October 18, 2022
This case study intends to demonstrate how effective surgical and physical therapy treatment can be provided to a patient who has suffered a serious spinal cord injury. Reducing the rate of death due ...
KEY FINDING: After two months of treatment, he was able to initiate the movement and he has achieved unsupported sitting.
Polymers, 2022 • October 17, 2022
This study developed a biomimetic scaffold composed of functionalized collagen-GMA hydrogel and aligned PCL/P11-8 electrospun nonwoven fibers to mimic the aligned structure of spinal cord tissue in vi...
KEY FINDING: Collagen-GMA hydrogels exhibited J-shaped stress–strain curves in compression, similar to native spinal cord tissue.
J. Funct. Morphol. Kinesiol., 2022 • October 17, 2022
This study investigates the effect of low force electrically induced exercise (LFE) on postprandial glycemic markers in individuals with spinal cord injury (SCI). The results indicate that LFE attenua...
KEY FINDING: People with SCI had higher fasting insulin, lactate, C-reactive protein, uric acid, alkaline phosphatase, and low-density lipoprotein compared to the non-SCI population.
Current Research in Neurobiology, 2022 • October 17, 2022
This review examines functional compensation following neural injury, focusing on motor and visual systems in nonhuman primates. After injury to novel neural systems, phylogenetically older systems ca...
KEY FINDING: After corticospinal tract lesions at C4-C5, propriospinal neurons contribute to the recovery of fractionated finger movements.
Materials Today Bio, 2022 • October 15, 2022
This study focuses on developing a bionic multichannel nanofiber conduit loaded with Tubastatin A (TUBA) to promote spinal cord repair. The conduit is designed to act as a bridge, supporting nerve cell...
KEY FINDING: The Tubastatin A-loaded nanofibers exhibited a sustained-release profile, meaning the drug was released slowly over time, maintaining its activity and promoting axonal extension.
Acta Biomater., 2022 • October 15, 2022
The BEACON system developed herein eliminates the need to target a cell or tissue receptor by targeting an implantable biomaterial with location-controllable accumulation and sustained presentation ov...
KEY FINDING: Demonstrated temporal dexterity in NP administration by injecting 6 days post-SCI.