Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 211-220 of 12,052 results
Stem Cell Research & Therapy, 2025 • January 21, 2025
This review provides a comprehensive overview of how mesenchymal stem cell-derived exosomes (MSC-Exos) regulate pyroptosis to alleviate bone-related diseases. It highlights the potential of MSC-Exos a...
KEY FINDING: MSC-Exos have low immunogenicity, are more accessible, have improved preservation qualities, and potentially have low carcinogenic risks compared to MSCs.
Curr. Issues Mol. Biol., 2025 • January 21, 2025
This review focuses on the therapeutic potential of miR-21 in the context of SCI, aiming to validate its neuroprotective role. The expression levels of miR-21 show variation in the different models of...
KEY FINDING: MiR-21 is upregulated in SCI and has protective effects on neurons through various mechanisms.
Journal of Rehabilitation Medicine, 2025 • January 21, 2025
Overall, studies indicate frequent participation in outdoor recreational activities like wheeling, hand- cycling, kayaking, and sit-skiing among people with SCI, offering positive experiences such as ...
KEY FINDING: People with SCI mainly report posi- tive experiences from engaging with the natural environment and pursuing outdoor activities, but also experienced a range of barriers that need to be considered in both research and clinical prac- tice.
Sensors, 2025 • January 21, 2025
This paper presents NeuroFlex, an EEG-based MI control system that controls a soft robotic glove for hand rehabilitation. NeuroFlex uses EEG data to interpret motor intent, converting them into real-t...
KEY FINDING: The accuracy of decoding the intent of fingers making a fist from MI EEG can reach up to 85.3%, with an average AUC of 0.88.
J. Clin. Med., 2025 • January 20, 2025
The aim of this study was to evaluate the effects of spinal cord stimulation (SCS) on pain, neuropathic symptoms, and other health-related metrics in patients with chronic painful peripheral neuropath...
KEY FINDING: SCS produced a significant consistent and sustained improvement in pain intensity by 49% in DN4 and 76% in VAS.
Nature Medicine, 2025 • January 20, 2025
The study presents a high-performance finger-based BCI system capable of decoding and controlling individual finger movements in an individual with tetraplegia. The system demonstrates continuous cont...
KEY FINDING: The developed BCI system allowed continuous control of three independent finger groups, with the thumb having two degrees of freedom, resulting in a total of four degrees of freedom.
Int. J. Mol. Sci., 2025 • January 19, 2025
This review discusses the principles and potential mechanisms of rTMS for treating SCI, including promoting the reconstruction of damaged circuits, activating cortical reorganization, modulating moton...
KEY FINDING: rTMS can promote activity-dependent regeneration of corticospinal tract (CST) axonal projections and the recruitment of propriospinal neurons and circuits.
Acta Neurochirurgica, 2025 • January 19, 2025
This study retrospectively reviewed data from 72 patients who underwent surgery for spinal schwannomas to identify factors associated with residual neurological deficits. The study found that thoracic...
KEY FINDING: Thoracic spine involvement is a significant risk factor for residual neurological deficits after surgery (OR, 5.03; 95% CI, 1.47–18.6; p = 0.01).
Cureus, 2025 • January 19, 2025
The study presents a simplified surgical technique for intrathecal baclofen (ITB) catheter replacement. It uses a 16-gauge peripheral vein catheter to guide the new catheter through the granulation tu...
KEY FINDING: The intrathecal catheter was successfully replaced through the granulation tunnel using a 16-gauge peripheral vein catheter as a guide.
Frontiers in Neuroscience, 2025 • January 17, 2025
The study investigates the impact of epidural ULF neuromodulation on thalamic neuron responses to peripheral sensory stimulation and pathological thalamic activity in a neuropathic pain model. Results...
KEY FINDING: ULF current can acutely and reversibly interrupt signaling between sensory afferent fibers and relay neurons of the thalamus.