Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 11,911-11,920 of 12,052 results
Neurorehabil Neural Repair, 2007 • January 1, 2007
This study demonstrated the concurrent and predictive validity of the Walking Index for Spinal Cord Injury (WISCI) scale in patients with incomplete spinal cord injury (SCI). The WISCI was significant...
KEY FINDING: Concurrent validity of the WISCI scale was supported by significant correlations with all measures at 3, 6, and 12 months.
Top Spinal Cord Inj Rehabil., 2007 • January 1, 2007
The Spinal Cord Injury Rehabilitation Evidence (SCIRE) is a synthesis of research evidence for rehabilitation interventions to improve the health of people with SCI. The SCIRE project used a systemati...
KEY FINDING: The SCIRE project identified areas where there is substantial quality evidence for practice and gaps where additional research is urgently needed.
Top Spinal Cord Inj Rehabil., 2007 • January 1, 2007
This systematic review assessed literature to provide clinical guidance for optimizing bone health after SCI, focusing on preventing acute bone loss and treating established low bone mass in long-stan...
KEY FINDING: Moderate evidence supports the use of pharmacology, particularly bisphosphonates, for treating bone loss after SCI.
Top Spinal Cord Inj Rehabil, 2007 • January 1, 2007
Rehabilitation strategies that facilitate repeated practice of gait offer the greatest benefits to functional ambulation in sub-acute or chronic SCI. Supportive devices may augment functional ambulati...
KEY FINDING: Body-weight supported treadmill training (BWSTT) is comparable to overground gait training in sub-acute SCI.
Top Spinal Cord Inj Rehabil, 2007 • January 1, 2007
The prevalence of obesity is increasing, including in individuals with spinal cord injuries (SCI). BMI may not accurately reflect obesity in SCI due to changes in body composition; percent body fat is...
KEY FINDING: Obesity prevalence may be underestimated or unclearly defined following SCI due to the lack of a valid differential tool.
Dev Biol, 2007 • January 1, 2007
This study investigates the role of apoptosis in tail regeneration in Xenopus laevis tadpoles. It finds that a specific amount of apoptosis is a required component of normal tail regeneration. The res...
KEY FINDING: Apoptosis is required for tail regeneration in Xenopus tadpoles.
Prog Brain Res, 2007 • January 1, 2007
This review focuses on transplantation studies using olfactory ensheathing cells (OEC) to improve functional outcome in experimental models of SCI and demyelination. Experimental work indicates that c...
KEY FINDING: Transplanted OECs can integrate into the injury site of a dorsal funiculus transection, distribute, associate longitudinally with axons spanning the lesion site, and form myelin.
Drug Discov Today Dis Models, 2007 • January 1, 2007
Mammals have a limited capacity for heart regeneration, unlike zebrafish. Zebrafish can regenerate heart tissue after injury, making them a valuable model for studying cardiac regeneration. Zebrafish ...
KEY FINDING: Zebrafish heart muscle can regenerate after injury with minimal scarring, replacing lost tissue with new contractile muscle.
Brain Res., 2006 • December 13, 2006
This study investigates the integration of transplanted olfactory ensheathing cells (OECs) into peripheral nerve injuries, specifically a sciatic nerve crush lesion in rats. The results show that tran...
KEY FINDING: Transplanted OECs survive in the lesion and distribute along regenerated axons in the peripheral nerve.
Cellular and Molecular Neurobiology, 2007 • December 7, 2006
The injured adult spinal cord is not conducive for neuronal regeneration and neurogenesis. Engrafted neural precursor cells (NPCs) differentiate largely into astroglia, with only a very small percenta...
KEY FINDING: Transplantation of ES cell-derived oligodendrocyte progenitor cells (OPCs) into contusion-injured adult rat spinal cord OPCs can differentiate into oligodendrocytes and improve locomotor ability if transplanted early after injury.