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  4. Validity of the Walking Scale for Spinal Cord Injury and Other Domains of Function in a Multicenter Clinical Trial

Validity of the Walking Scale for Spinal Cord Injury and Other Domains of Function in a Multicenter Clinical Trial

Neurorehabil Neural Repair, 2007 · DOI: 10.1177/1545968307301880 · Published: January 1, 2007

Spinal Cord InjuryRehabilitationResearch Methodology & Design

Simple Explanation

This study checks if a walking test, called the Walking Index for Spinal Cord Injury (WISCI), accurately measures walking ability in people with spinal cord injuries. Researchers compared the WISCI with other tests that measure strength, balance, walking speed, and how well people can function in daily life to see if they all agree. The study found that the WISCI does a good job of measuring walking ability and that strength in the legs is a key factor in how well someone can walk after a spinal cord injury.

Study Duration
12 weeks intervention, 12 months follow-up
Participants
146 patients with incomplete SCI (C4 to L3)
Evidence Level
Level 1, Prospective multicenter clinical trial

Key Findings

  • 1
    Concurrent validity of the WISCI scale was supported by significant correlations with all measures at 3, 6, and 12 months.
  • 2
    The LEMS at baseline was the best predictor of the WISCI score at 12 months and explained most of the variance, which supported both predictive and construct validity.
  • 3
    The combination of the LEMS, BBS, WISCI, 50FW-S, and LFIM appears to encompass adequate descriptors for outcomes of walking trials for incomplete SCI.

Research Summary

This study demonstrated the concurrent and predictive validity of the Walking Index for Spinal Cord Injury (WISCI) scale in patients with incomplete spinal cord injury (SCI). The WISCI was significantly correlated with other measures of impairment (LEMS), functional capacity (BBS, 50FW-S, 6MW-D), and disability (LFIM, FIM) at 3, 6, and 12 months. Baseline LEMS was found to be the best predictor of WISCI score at 12 months, supporting the predictive and construct validity of the WISCI scale.

Practical Implications

Clinical Trial Design

The WISCI scale is a valid and reliable outcome measure for walking ability in clinical trials for incomplete SCI.

Prognostic Value

Baseline LEMS can be used to predict walking outcomes in patients with incomplete SCI.

Comprehensive Assessment

A combination of LEMS, BBS, WISCI, 50FW-S, and LFIM provides a comprehensive assessment of walking ability in incomplete SCI.

Study Limitations

  • 1
    The study population was limited to patients with incomplete SCI.
  • 2
    Baseline values of some measures clustered at the lower range, potentially affecting their predictive ability.
  • 3
    The study could not determine whether one measure of efficacy would be more useful than another.

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