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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Latest Research Summaries

Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.

Showing 11,721-11,730 of 12,052 results

TraumaRehabilitation

Ten years of major equestrian injury: are we addressing functional outcomes?

Journal of Trauma Management & Outcomes, 2009 • February 19, 2009

This study aimed to define the incidence and pattern of severe equestrian trauma, identify the current level of in-patient rehabilitation services, describe functional outcomes for patients, and discu...

KEY FINDING: Rehabilitation therapy is underutilized following severe equestrian trauma.

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NeurologyNeuroplasticity

Plasticity in neurological disorders and challenges for noninvasive brain stimulation (NBS)

Journal of NeuroEngineering and Rehabilitation, 2009 • February 17, 2009

Noninvasive brain stimulation (NBS) is being investigated for neurological conditions, with the understanding that it can modulate neuroplasticity. Plasticity is considered crucial for functional reco...

KEY FINDING: Neuroplasticity, involving both neuronal and non-neuronal mechanisms, plays a significant role in brain function, with synaptic transmission being a key site for plasticity.

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NeurologySurgerySpinal Disorders

Is extensive cervical laminoplasty an effective treatment for spinal cord sarcoidosis combined with cervical spondylosis?

Eur Spine J, 2009 • February 12, 2009

The study evaluates the effectiveness of extensive cervical laminoplasty for spinal cord sarcoidosis combined with spondylotic changes. The results showed unsatisfactory operative outcomes and fluctua...

KEY FINDING: Operative outcomes following laminoplasty were not satisfactory in patients with spinal cord sarcoidosis combined with cervical spondylosis.

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Spinal Cord InjuryImmunology

Mechanisms and implications of adaptive immune responses after traumatic spinal cord injury

Neuroscience, 2009 • February 6, 2009

Traumatic SCI triggers autoimmune reactions involving T and B cells, influencing post-traumatic inflammation, neurodegeneration, and repair processes. These lymphocytes are activated by SCI and play s...

KEY FINDING: SCI activates MBP-reactive T cells capable of causing neuroinflammation and transient paralysis in rats, and the frequency of MBP-reactive T cells increases in SCI humans, reaching levels that approximate those seen in MS patients.

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Spinal Cord InjuryUrologyNeurology

Bladder Inhibition or Excitation by Electrical Perianal Stimulation in the Chronic SCI Cat

BJU Int, 2009 • February 1, 2009

The study investigated the effects of perianal electrical stimulation on bladder function in chronic spinal cord injured (SCI) cats. Frequency-dependent inhibitory or excitatory reflex bladder respons...

KEY FINDING: Electrical perianal stimulation at frequencies between 3 Hz and 10 Hz significantly inhibited large amplitude reflex bladder activity.

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Spinal Cord InjuryRehabilitationDermatology

A Systematic Review of Therapeutic Interventions for Pressure Ulcers Following Spinal Cord Injury

Arch Phys Med Rehabil, 2009 • February 1, 2009

Pressure ulcers remain a common and potentially serious lifelong secondary complication of SCI, impacting overall quality of life and disrupting various aspects of an individual's life. Many preventio...

KEY FINDING: Electrical stimulation may decrease ischial pressures and increase blood flow in sacral and gluteal areas, potentially aiding in pressure ulcer prevention.

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Spinal Cord InjuryCardiovascular ScienceRehabilitation

Venous Thromboembolism Following Spinal Cord Injury

Arch Phys Med Rehabil, 2009 • February 1, 2009

This systematic review examined the treatment of venous thromboembolism in SCI patients, finding good evidence for pharmacological prophylaxis. Research into non-pharmacological prophylaxis or treatm...

KEY FINDING: Low molecular weight heparin (LMWH) is more effective than unfractionated heparin (UFH) in preventing venous thromboembolic events and has a lower risk of bleeding complications.

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Spinal Cord InjuryNeurologyRehabilitation

Implanted Electrical Stimulation of the Trunk for Seated Postural Stability and Function after Cervical SCI: A Single Case Study

Arch Phys Med Rehabil, 2009 • February 1, 2009

This single-subject case study investigated the effects of an implanted neuroprosthesis on seated postural stability and function in an individual with C4 ASIA A tetraplegia. The neuroprosthesis deliv...

KEY FINDING: Electrical stimulation improved spinal alignment, reducing spinal convexity and kyphosis. Specifically, spinal convexity improved by 26° and kyphosis by 21°.

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Biomedical

Adaptive Control of Movement for Neuromuscular Stimulation-Assisted Therapy in a Rodent Model

IEEE Trans Biomed Eng, 2009 • February 1, 2009

This study implemented an adaptive control system in a rodent model for neuromotor therapy to address the shortcomings of previous open-loop control systems, which were unable to generate accurate mov...

KEY FINDING: The adaptive PG/PS control system provided excellent movement tracking with less than 10% error in 100-cycle movement trials, although stimulation levels increased to counteract muscle fatigue.

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Regenerative MedicineNeurologyGenetics

Generation of spinal motor neurons from human fetal brain-derived neural stem cells: role of basic fibroblast growth factor

J Neurosci Res, 2009 • February 1, 2009

This study demonstrates that human fetal cortical NSCs can be induced to express spinal motor neuron characteristics in vitro by bFGF. bFGF enhances the expression of ventral markers such as Olig2 in ...

KEY FINDING: bFGF induces human NSCs to express the motor neuron marker Hb9.

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