Spinal Cord Research Help
AboutCategoriesLatest ResearchContact
Subscribe
Spinal Cord Research Help

Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

Quick Links

  • Home
  • About
  • Categories
  • Latest Research
  • Disclaimer

Contact

  • Contact Us
© 2025 Spinal Cord Research Help

All rights reserved.

  1. Home
  2. Research
  3. Neurology
  4. Is extensive cervical laminoplasty an effective treatment for spinal cord sarcoidosis combined with cervical spondylosis?

Is extensive cervical laminoplasty an effective treatment for spinal cord sarcoidosis combined with cervical spondylosis?

Eur Spine J, 2009 · DOI: 10.1007/s00586-009-0891-2 · Published: February 12, 2009

NeurologySurgerySpinal Disorders

Simple Explanation

This study investigates the effectiveness of extensive cervical laminoplasty for treating spinal cord sarcoidosis combined with spondylotic changes or cervical spinal canal stenosis. Three patients with spinal cord sarcoidosis underwent open-door laminoplasty and intensive corticosteroid therapy. The study found that operative outcomes were not satisfactory and clinical courses fluctuated after steroid treatment. The authors suggest that spinal cord sarcoidosis should be considered in differential diagnoses when MRI shows high signal intensity within the spinal cord in patients with spondylotic changes and that laminoplasty is not effective for treating spinal cord sarcoidosis in these cases.

Study Duration
Not specified
Participants
Three patients with spinal cord sarcoidosis
Evidence Level
Not specified

Key Findings

  • 1
    Operative outcomes following laminoplasty were not satisfactory in patients with spinal cord sarcoidosis combined with cervical spondylosis.
  • 2
    Daily life activities were not significantly improved after treatments in any of the three patients.
  • 3
    In one patient, the clinical course deteriorated to quadriplegia despite treatment.

Research Summary

The study evaluates the effectiveness of extensive cervical laminoplasty for spinal cord sarcoidosis combined with spondylotic changes. The results showed unsatisfactory operative outcomes and fluctuating clinical courses after corticosteroid therapy in three patients. The authors conclude that laminoplasty is not an effective intervention for spinal cord sarcoidosis, even with spondylotic changes, and recommend prioritizing steroid administration.

Practical Implications

Diagnostic Consideration

Spinal cord sarcoidosis should be considered in the differential diagnosis when MRI shows high signal intensity within the spinal cord in patients with spondylotic changes.

Treatment Approach

Patients with neurosarcoidosis, even with cord compression, should initially be treated with steroid administration rather than laminoplasty.

Surgical Intervention

Laminoplasty is not recommended as an effective intervention for the treatment of spinal cord sarcoidosis, even when patients have spondylotic changes.

Study Limitations

  • 1
    Small sample size of only three patients.
  • 2
    Lack of a control group.
  • 3
    Not specified

Your Feedback

Was this summary helpful?

Back to Neurology