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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Latest Research Summaries

Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.

Showing 11,711-11,720 of 12,052 results

NeuroimagingNeurologyNeurorehabilitation

Cortical and Subcortical Correlates of Functional Electrical Stimulation of Wrist Extensor and Flexor Muscles Revealed by fMRI

Hum Brain Mapp, 2009 • March 1, 2009

This study investigates the feasibility and reliability of using functional electrical stimulation (FES) in an MRI environment to observe brain activity. The experiment involved alternating stimulatio...

KEY FINDING: FES stimulation reliably activates the sensorimotor network, including the contralateral primary motor cortex, somatosensory cortex, and premotor cortex.

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Spinal Cord InjuryMusculoskeletal Medicine

Osteoporotic fractures and hospitalization risk in chronic spinal cord injury

Osteoporos Int, 2009 • March 1, 2009

This study prospectively assessed risk factors for hospitalization due to low-impact fractures in individuals with chronic SCI. It found a significant association between motor complete SCI and greate...

KEY FINDING: Motor complete spinal cord injury is an independent risk factor for hospitalization due to low-impact fractures.

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Spinal Cord InjuryPediatricsRehabilitation

Motor Scores on the Functional Independence Measure (FIM) After Pediatric Spinal Cord Injury (SCI)

Spinal Cord, 2009 • March 1, 2009

This study reports on the functional ability of children with spinal cord injury (SCI) as recorded on motor items of the functional independence measure (FIM) and examines factors associated with FIM ...

KEY FINDING: FIM motor scores at admission were negatively correlated with age, neurological level, and completeness of injury, indicating that older children and those with more severe injuries had lower initial scores.

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Spinal Cord InjuryRehabilitationMusculoskeletal Medicine

Physiatrists’ Opinions and Practice Patterns for Bone Health after SCI

Spinal Cord, 2009 • March 1, 2009

This survey of Canadian physiatrists reveals their opinions and practices regarding bone health management after spinal cord injury (SCI). The study highlights that while physiatrists recognize the im...

KEY FINDING: Most physiatrists believe they should manage bone health issues after SCI in conjunction with family physicians.

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PediatricsNeurorehabilitationRehabilitation

A Systematic Review of the Effectiveness of Treadmill Training and Body Weight Support in Pediatric Rehabilitation

J Neurol Phys Ther, 2009 • March 1, 2009

This systematic review evaluated the evidence supporting treadmill training with and without body weight support for children and young adults (under 21 years) with motor disabilities, including cereb...

KEY FINDING: Treadmill training is effective in accelerating walking development in children with Down syndrome.

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Spinal Cord InjuryHealthcareMusculoskeletal Medicine

VA-Based Survey of Osteoporosis Management in Spinal Cord Injury

PM R, 2009 • March 1, 2009

The study aimed to characterize osteoporosis management practices in SCI patients within the VA healthcare system due to the absence of established guidelines. A web-based survey was distributed to VH...

KEY FINDING: More than half of the respondents (54%) actively prescribe medications for SCI-induced bone loss, with bisphosphonates and vitamin D being the most common choices.

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NeurologyNeurorehabilitation

Novel Multi-Modal Strategies to Promote Brain and Spinal Cord Injury Recovery

Stroke, 2009 • March 1, 2009

The review addresses the need for multi-modal strategies to promote brain and spinal cord injury recovery, focusing on the limitations of current interventions and the potential of combining neuroprot...

KEY FINDING: The research identified nearly 10 FDA-approved compounds capable of simultaneously activating protective and reparative genes, suggesting a broad therapeutic window spanning from acute to chronic injury stages.

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Spinal Cord InjuryNeurologyGenetics

Mouse olfactory ensheathing glia enhance axon outgrowth on a myelin substrate in vitro

Exp Neurol, 2009 • March 1, 2009

This study developed an in vitro model to examine the ability of olfactory bulb-derived OEG to promote axon regeneration of DRG neurons on a myelin substrate. The results showed that OEG promote a hig...

KEY FINDING: OEG enhance DRG axon outgrowth on myelin: More neurons generate axons, and their average length is almost twice that of those grown on myelin alone.

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Regenerative MedicineNeurology

Expression of the regeneration-associated protein SPRR1A in primary sensory neurons and spinal cord of the adult mouse following peripheral and central injury

J Comp Neurol, 2009 • March 1, 2009

This study characterized SPRR1A expression in the DRG and spinal cord of adult mice following injury to the peripheral and central projections of DRG neurons, finding that SPRR1A induction correlates ...

KEY FINDING: SPRR1A expression is minimal following injury to the centrally projecting branches of DRG neurons.

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NeurologyBrain Injury

Protection in Animal Models of Brain and Spinal Cord Injury with Mild to Moderate Hypothermia

JOURNAL OF NEUROTRAUMA, 2009 • March 1, 2009

Mild to moderate hypothermia has shown promise in protecting the brain and spinal cord after injury in animal models. The mechanisms behind hypothermic protection involve various cellular, biochemical...

KEY FINDING: Mild hypothermia can improve functional outcomes in transient global ischemia models, including sensorimotor and cognitive functions.

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