Browse the latest research summaries in the field of urology for spinal cord injury patients and caregivers.
Showing 391-400 of 407 results
J. Clin. Med., 2024 • March 8, 2024
This meta-analysis provides the summary estimates for perioperative and postoperative functional outcome and safety of endoscopic treatment options for BPO in patients ≥75 years of age. Of particular ...
KEY FINDING: All surgical techniques significantly improve the postoperative quality of life of patients in this age group compared to their preoperative quality of life.
J Urol, 2015 • June 1, 2015
This study investigates whether the reinnervated neuronal pathway mediates contraction via the same neurotransmitter and receptor mechanisms as the original pathway. In contrast, SCh virtually elimina...
KEY FINDING: Succinylcholine (SCh) virtually eliminated bladder pressure increases induced by electrical stimulation of the transferred somatic nerves or the lumbar spinal segments that contribute axons to these donor nerves.
The Journal of Spinal Cord Medicine, 2015 • November 1, 2015
This study aimed to reconstruct a bladder reflex arc with both afferent and efferent pathways to achieve atonic bladder innervation after SCI. The bladder reflex arc with afferent and efferent pathway...
KEY FINDING: The study successfully reconstructed a bladder reflex arc with both afferent and efferent pathways in rats with spinal cord injury.
The Journal of Neuroscience, 2015 • February 4, 2015
This study investigates the role of BDNF in the development and maintenance of NDO after spinal cord injury (SCI) in rats. The findings suggest that BDNF plays a complex and potentially dual role in N...
KEY FINDING: Spinal BDNF expression increased in a time-dependent manner after SCI, correlating with the emergence of NDO.
Research and Reports in Urology, 2016 • September 28, 2016
The study successfully developed a CT-guided technique for tined lead implantation in minipigs for sacral neuromodulation. The procedure allows for precise targeting of the sacral nerve root S3, leadi...
KEY FINDING: Successful bilateral tined lead implantation was achieved in four out of five minipigs using the CT-guided technique.
Int Neurourol J, 2017 • March 1, 2017
This study aimed to determine the structural changes of the urinary bladder after chronic SCI in minipigs, with a focus on the analysis of urinary bladder wall proteins and their quantitative distribu...
KEY FINDING: Chronic SCI significantly increased bladder wall thickness in minipigs.
Neural Regeneration Research, 2017 • February 1, 2017
This study investigates the effects of Tanshinone IIA (TIIA) on lower urinary tract (LUT) dysfunction in a rat model of spinal cord injury (SCI). The results indicate that TIIA treatment improves blad...
KEY FINDING: TIIA reduced inflammation and edema in the bladder tissue of SCI rats.
Journal of Medical Case Reports, 2017 • November 27, 2017
This case report details the successful use of human umbilical cord mesenchymal stem cells (hUC-MSCs) to treat a 62-year-old woman with chronic renal failure and thoracic spinal cord entrapment. The p...
KEY FINDING: After hUC-MSC treatment, the patient could move her toes three weeks after the first intrathecal and intravenous implantation.
Journal of Visualized Experiments, 2018 • January 30, 2018
This article describes a surgical and measurement protocol for assessing lower urinary tract function in awake rats, using implanted catheters and electrodes to simultaneously monitor the urinary blad...
KEY FINDING: The success rate for the surgical procedure and maintaining the implanted devices intact is approximately 80%.
J Neurosurg Spine, 2019 • November 8, 2019
The study aimed to determine if nerve transfer after long-term decentralization restores bladder and sphincter function in canines. The results showed that new neuronal pathways created by nerve trans...
KEY FINDING: Transection of L7 dorsal roots was necessary for significant reduction of squat-and-void postures after sacral root transection.