Browse the latest research summaries in the field of urology for spinal cord injury patients and caregivers.
Showing 301-310 of 407 results
Ann Rehabil Med, 2011 • October 1, 2011
This study evaluated the effect of semiconditional electrical stimulation of the pudendal nerve afferents for neurogenic detrusor overactivity in patients with spinal cord injury. Semiconditional stim...
KEY FINDING: Among the 40 subjects, 35 patients showed neurogenic detrusor overactivity in the CMG study. Among these 35 patients, detrusor overactivity was suppressed eff ectively by pudendal nerve aff erent electrical stimulation in 32 patients.
The Journal of Spinal Cord Medicine, 2018 • July 1, 2018
This study investigated the effect of oral probenecid on sperm motility in men with SCI, finding a statistically significant improvement. Probenecid, a pannexin-1 channel blocker, is hypothesized to i...
KEY FINDING: Sperm motility improved in each subject after 4 weeks of oral probenecid.
Spinal Cord Series and Cases, 2017 • May 4, 2017
This study evaluated the diagnostic accuracy of single-channel cystometry (SCC) for confirming neurogenic bladder following spinal cord injury (SCI). Sixteen patients with a clinical diagnosis of neur...
KEY FINDING: SCC has a high sensitivity (100%) and negative predictive value (100%) for diagnosing neurogenic bladder, but a lower specificity (50%). This means that SCC is good at identifying patients who have neurogenic bladder and correctly ruling out those who don't, but it may have false positives.
Spinal Cord Series and Cases, 2017 • May 11, 2017
This case report describes the successful use of ceftolozane/tazobactam (C/T) to treat a febrile urinary tract infection (UTI) caused by multidrug-resistant (MDR) Pseudomonas aeruginosa (PSA) in a 35-...
KEY FINDING: Ceftolozane/tazobactam was effective in treating a febrile UTI caused by multidrug-resistant Pseudomonas aeruginosa in a patient with a neurogenic bladder.
Ann Rehabil Med, 2017 • April 1, 2017
This case report details an instance of contrast material extravasation during VCUG in a 59-year-old female with paraplegia due to tuberculous spondylitis. The extravasation occurred without manual in...
KEY FINDING: The study reports a rare case of extraperitoneal bladder rupture with spontaneous healing in a spinal cord injury patient without manual instillation during VCUG.
Spinal Cord Series and Cases, 2017 • May 25, 2017
The study assessed the prevalence of sexual and fertility dysfunction in men with traumatic SCI in Jamaica. The results revealed a high prevalence of erectile and ejaculatory dysfunction, coupled with...
KEY FINDING: 90.7% of men with traumatic SCI experienced erectile dysfunction, with 62.8% classified as severe.
TheScientificWorldJOURNAL, 2007 • October 22, 2007
The study compared intravesical oxybutynin, propantheline, and capsaicin for treating neurogenic detrusor overactivity (NDO) following spinal cord injury (SCI). Capsaicin showed statistically signific...
KEY FINDING: Intravesical capsaicin significantly improved reflex volume, cystometric capacity, leak volume, and leak frequency in treating neurogenic detrusor overactivity.
J Neural Eng, 2007 • December 1, 2007
This study evaluated the effects of intraspinal microstimulation on bladder voiding in cats before and after spinal cord injury. Microelectrode arrays were implanted in the sacral spinal cord to stimu...
KEY FINDING: Stimulation at the S1 level produced strong bladder contractions and EUS relaxation, resulting in voiding in 14 animals.
J Mol Neurosci, 2008 • November 1, 2008
Vasoactive intestinal polypeptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) are expressed in the neural pathways regulating the lower urinary tract. VIP-immunoreactivity (IR...
KEY FINDING: Exogenously applied VIP relaxes bladder and urethral smooth muscle and excites parasympathetic neurons in bladder ganglia.
BJU Int, 2009 • February 1, 2009
The study investigated the effects of perianal electrical stimulation on bladder function in chronic spinal cord injured (SCI) cats. Frequency-dependent inhibitory or excitatory reflex bladder respons...
KEY FINDING: Electrical perianal stimulation at frequencies between 3 Hz and 10 Hz significantly inhibited large amplitude reflex bladder activity.