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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Surgery Research

Browse the latest research summaries in the field of surgery for spinal cord injury patients and caregivers.

Showing 231-240 of 614 results

Spinal Cord InjuryPain ManagementSurgery

The impact of time from injury to surgery on the risk of neuropathic pain after traumatic spinal cord injury

Journal of Orthopaedic Surgery and Research, 2023 • November 7, 2023

This retrospective study investigated the impact of time from injury to surgery on neuropathic pain (NeP) development after traumatic spinal cord injury (SCI). The study found that delayed surgical in...

KEY FINDING: Age at injury, Injury Severity Score, and neurological level of injury are independent risk factors for the development of NeP in both AIS A and AIS B, C, and D subgroups.

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OncologySurgery

Transient spinal cord dysfunction after surgery for intraspinal tumors: A case report

Medicine, 2023 • November 3, 2023

This case report describes a 73-year-old female patient who experienced transient unilateral limb dysfunction following surgery for a thoracic spinal meningioma. The patient presented with numbness an...

KEY FINDING: Transient unilateral limb dysfunction can occur after surgery for intraspinal meningiomas, even without apparent spinal cord injury during the procedure.

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NeurologySurgery

Simultaneous upper and lower body perfusion using hypothermia during thoracoabdominal aortic surgery

Journal of Cardiothoracic Surgery, 2023 • November 4, 2023

This study investigates the effectiveness of simultaneous upper and lower body perfusion under moderate to deep hypothermia during thoracoabdominal aortic aneurysm (TAAA) repair. The technique aims to...

KEY FINDING: No patients developed paraplegia, paraparesis, or other nerve damage due to SCII or cerebral infarction.

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NeurologyGeneticsSurgery

The molecular landscape of neurological disorders: insights from single-cell RNA sequencing in neurology and neurosurgery

European Journal of Medical Research, 2023 • November 3, 2023

ScRNA-seq has emerged as a powerful tool that has revolutionised our understanding of neurological disorders, providing high-resolution insights into cellular heterogeneity and gene expression profile...

KEY FINDING: In recurrent glioblastoma multiforme (GBM), scRNA-seq analysis revealed overexpression of stemness and cell-cycle-related genes, decreased microglial proportions, high expression of vascular endothelial growth factor A (VEGF-A), increased blood–brain barrier permeability, and activation of the O6-methylguanine deoxyribonucleic acid (DNA) methyltransferase-related pathway.

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ImmunologySurgery

Mimicking Clinical Rejection Patterns in a Rat Osteomyocutaneous Flap Model of Vascularized Composite Allotransplantation

J Surg Res, 2024 • March 1, 2024

The study presents a rat osteomyocutaneous flap model for VCA that mimics clinical rejection patterns through titrated tacrolimus administration. The model allows for the study of acute rejection, chr...

KEY FINDING: Transient immunosuppression resulted in severe acute cellular rejection within two weeks of tacrolimus discontinuation, mimicking non-compliance situations.

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Spinal Cord InjurySurgeryPalliative Care

Factors influencing withdrawal of life‑supporting treatment in cervical spinal cord injury: a large multicenter observational cohort study

Critical Care, 2023 • November 8, 2023

This multicenter study identified factors associated with WLST in patients with complete cervical SCI. These factors include patient demographics like age, sex, race, and insurance, as well as injury-...

KEY FINDING: Advanced age, male sex, white race, prior dementia, low Glasgow Coma Scale score, pre-hospital cardiac arrest, SCI level of C3 or above, and concurrent severe head or thorax injury were associated with increased likelihood of WLST.

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SurgeryOrthopedicsMusculoskeletal Medicine

Comparison of percutaneous vertebroplasty and conservative treatment for one level thoracolumbar osteoporotic compression fracture in a 3‑year study

Scientific Reports, 2023 • December 1, 2023

The study evaluated mesh-optimized PVP against traditional PVP for osteoporotic vertebral compression fractures, finding the optimized method superior. Mesh-optimized PVP demonstrated shorter operatio...

KEY FINDING: Mesh optimization group had improved operation time (34.8 ± 6.5 min) compared to traditional PVP group (42.7 ± 8.2) min.

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OncologySurgery

Reevaluating age restrictions of spinal metastasis surgery in elderly groups with over 2‑year follow‑up

Neurosurgical Review, 2023 • November 21, 2023

This study compares surgical outcomes in elderly patients (65–79 years vs. ≥ 80 years) undergoing laminectomy for spinal metastasis with epidural spinal cord compression (MESCC). The research found th...

KEY FINDING: Octogenarians had significantly higher age-adjusted Charlson Comorbidity Index (CCI) scores compared to the 65–79 age group, indicating a greater burden of comorbidities.

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AgingSurgeryOrthopedics

Early Stabilization Does Not Increase Complication Rates in Acetabular Fractures of the Elderly: A Retrospective Analysis from the German Pelvis Registry

J. Clin. Med., 2023 • November 11, 2023

This retrospective study analyzed data from the German Pelvis Registry between 2008 and 2017, focusing on acetabular fractures in patients over and under 65 years old. The study aimed to determine if ...

KEY FINDING: The complication rate of the geriatric group was twice as high as that of younger patients; however, this finding was independent of the timing of surgery.

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PhysiologySurgeryOrthopedics

A Retrospective Study of Degenerative Cervical Myelopathy and the Surgical Management Within Northern Ireland

Cureus, 2023 • November 27, 2023

This retrospective study evaluated the surgical management of degenerative cervical myelopathy (DCM) in Northern Ireland over three years, with a one-year follow-up, using data from the Fracture Outco...

KEY FINDING: The mJOA score tends to improve after surgery for the majority of patients, particularly at six months, which is consistent with the literature.

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