Browse the latest research summaries in the field of research methodology & design for spinal cord injury patients and caregivers.
Showing 681-690 of 702 results
Neural Regen Res, 2019 • January 1, 2019
This review examines the differences in neuroplasticity following spinal cord injury (SCI) among animal models and humans, highlighting variations in sensorimotor pathways and recovery rates. It discu...
KEY FINDING: Rats regain weight-bearing abilities without interventions two weeks post-injury, unlike humans.
Neural Regen Res, 2019 • April 1, 2019
This study aimed to establish and verify a surgical prognostic model for cervical spinal cord injury without radiological abnormality. The model uses factors like cervical stenosis, JOA score, and dis...
KEY FINDING: A prognostic model was established: logit(P) = −25.4545 + 21.2576VALUE + 1.2160SCORE − 3.4224TIME, where VALUE is the Pavlov ratio, SCORE is the JOA score, and TIME is disease duration.
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2019 • January 16, 2019
This study investigated the axolotl's ability to regenerate from a clinically relevant blunt spinal cord injury. Axolotls were subjected to a contusion SCI, and their regeneration was assessed using M...
KEY FINDING: Axolotls are capable of morphologically regenerating the spinal cord following a contusion trauma.
Journal of Biological Engineering, 2019 • May 7, 2019
The study investigates the effect of low-frequency vibration on the formation of olfactory ensheathing cell (OEC) spheroids in naked liquid marble (NLM) cultures, aiming to improve cell transplantatio...
KEY FINDING: Vibrating naked liquid marbles (NLMs) containing OECs at different frequencies significantly impacted spheroid size and number, with 60 Hz causing the most dramatic increase in spheroid volume.
Med Sci Monit, 2019 • June 24, 2019
This study evaluated prognostic factors for overall survival (OS) and cause-specific survival (CSS) in patients with non-metastatic osteosarcoma using the SEER database. Multivariable analysis identif...
KEY FINDING: Age, tumor size, grade, and AJCC T staging were independent prognostic factors for OS and CSS.
J Evid Based Med, 2019 • September 1, 2019
This systematic review aimed to determine the median sample size in clinical trials involving individuals with spinal cord injury (SCI) and to examine the statistical methods used in small-sample size...
KEY FINDING: The median total sample size across the included studies was 18 individuals.
Scientific Reports, 2019 • June 13, 2019
The study aimed to validate a fetal lamb model for spina bifida (SB) research, comparing two surgical models (with and without myelotomy) to normal lambs. The myelotomy model best phenocopied the anat...
KEY FINDING: The myelotomy model best replicates the anatomy, pathophysiology, and symptoms of non-cystic spina bifida (SB).
Neural Regen Res, 2020 • April 1, 2020
This study aimed to establish a rat spinal cord injury (SCI) model with a closed spinal canal to investigate the differences in neurological dysfunction and pathological changes compared to open canal...
KEY FINDING: The Basso-Beattie-Bresnahan (BBB) scores were significantly lower in the closed canal group compared to the open canal group, indicating greater neurological dysfunction.
Orthopaedic Surgery, 2019 • October 1, 2019
This study aimed to identify prognostic factors and develop nomograms for predicting the overall survival (OS) and cause-specific survival (CSS) of patients with non-metastatic chondrosarcoma using da...
KEY FINDING: Age, gender, tumor size and extension, surgery, histological grade, and subtype were identified as independent prognostic factors for both overall survival (OS) and cause-specific survival (CSS).
PLoS ONE, 2019 • November 22, 2019
This study analyzes the relationship between journal size and the longitudinal variability of the Journal Impact Factor (JIF) using a comprehensive dataset of journals from the Incite Journal Citation...
KEY FINDING: Larger journals generally exhibit smaller annual changes in their Journal Impact Factor (JIF) compared to smaller journals, indicating greater stability.