Browse the latest research summaries in the field of research methodology & design for spinal cord injury patients and caregivers.
Showing 521-530 of 702 results
Spinal Cord, 2018 • December 28, 2017
This review discusses important features of clinical outcomes assessments (COAs) in human spinal cord injury research. It presents considerations for COAs by trial phase and International Classificati...
KEY FINDING: COAs should be appropriate for the trial phase, distinguishing between recovery and compensation, and clinically meaningful.
BMC Psychology, 2018 • January 8, 2018
This qualitative study explored narratives of resilience among seven males living with spinal cord injury (SCI), revealing how they sustain long-term wellbeing. Key findings highlighted the importance...
KEY FINDING: Participants highlighted the importance of positive thinking, determination, and self-responsibility in maintaining emotional stability and overall wellbeing after a spinal cord injury.
Scientific Reports, 2018 • January 10, 2018
This meta-analysis evaluated the effects of OEC transplantation on neuropathic pain for the first time, finding that longer follow-up periods were associated with reports of OEC transplantation negati...
KEY FINDING: OEC transplantation significantly improves functional recovery post-SCI in animal models.
Top Spinal Cord Inj Rehabil, 2017 • January 1, 2017
The study aimed to investigate the quality and quantity of clinical NTSCI evidence published in peer-reviewed journals, covering various research domains. The review identified gaps in qualitative, me...
KEY FINDING: Prognostics had adequate data yield for evidence synthesis, with 4.8% ranked level 1A or 11A.
Top Spinal Cord Inj Rehabil, 2017 • January 1, 2017
This study validated an algorithm for identifying persons with non-traumatic spinal cord dysfunction (NTSCD) using administrative health data in Alberta, Canada. The algorithm demonstrated high sensit...
KEY FINDING: The algorithm has high sensitivity (97%) and positive predictive value (PPV) (92%) for identifying NTSCD cases.
Surgical Neurology International, 2018 • January 16, 2018
This case report describes a 14-year-old male who developed acute tetraplegia following laryngotracheal reconstruction surgery, attributed to potential spinal cord ischemia. The patient exhibited a C4...
KEY FINDING: The patient presented with acute tetraplegia, sensory loss below C4, and bowel/bladder dysfunction following laryngotracheal reconstruction.
Spinal Cord Series and Cases, 2017 • August 31, 2017
The Austrian Spinal Cord Injury Study (ASCIS) collects longitudinal data on simple forms within a 7-stage follow-up examination timeline. ASCIS is uniquely positioned in Austria to capture detailed in...
KEY FINDING: The implementation of the ASCIS in 2012 created the first nationwide SCI patient registry in Austria.
PLoS ONE, 2018 • February 23, 2018
This systematic review and meta-analysis examined VO2peak values in Paralympic sitting sports to understand sport-specific aerobic demands and the influence of various factors on VO2peak. The review i...
KEY FINDING: The highest VO2peak values were observed in Nordic sit skiing, reflecting the high aerobic demands of this endurance sport.
The Journal of Spinal Cord Medicine, 2019 • January 1, 2019
Current treatment of spinal cord injury (SCI) focuses on cord stabilization to prevent further injury, rehabilitation, management of non-motor symptoms, and prevention of complications. There is urgen...
KEY FINDING: There is urgent need to develop disease-modifying therapy for SCI, yet the commercial landscape remains small and highly fragmented with a paucity of novel late-stage compounds in R&D.
Top Spinal Cord Inj Rehabil, 2018 • January 1, 2018
This study investigated racial/ethnic differences in response completeness within a longitudinal spinal cord injury (SCI) database, including 7,507 participants. The study found that missing data rate...
KEY FINDING: The overall missing data rate was significant across several measures, including economic self-sufficiency, alcohol use, drug use, life satisfaction, depression, and pain severity.