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Research Methodology & Design Research

Browse the latest research summaries in the field of research methodology & design for spinal cord injury patients and caregivers.

Showing 361-370 of 702 results

Spinal Cord InjuryBioinformaticsResearch Methodology & Design

Baseline-adjusted proportional odds models for the quantification of treatment effects in trials with ordinal sum score outcomes

BMC Medical Research Methodology, 2020 • May 7, 2020

The paper introduces baseline-adjusted proportional odds models for analyzing ordinal outcomes in clinical trials, addressing limitations of conventional methods. A simulation study demonstrated the s...

KEY FINDING: The simulation study demonstrated that the statistical power of the novel method was greater than that of conventional methods.

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NeurologySpinal DisordersResearch Methodology & Design

Acute spinal subdural hematoma A case report of spontaneous recovery from paraplegia

Medicine, 2020 • May 8, 2020

This case report describes a 59-year-old male who presented with sudden back pain and paraplegia due to a spontaneous spinal subdural hematoma (SSDH). The patient was treated conservatively with bed r...

KEY FINDING: Chronological MRI scans depicted a spontaneous decrease in the hematoma only two days after the presentation of paraplegia.

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Spinal Cord InjuryResearch Methodology & DesignPublic Health

Understanding how a community-based intervention for people with spinal cord injury in Bangladesh was delivered as part of a randomised controlled trial: a process evaluation

Spinal Cord, 2020 • June 15, 2020

This study examined the implementation of a community-based model of care for individuals with SCI in Bangladesh, focusing on the experiences of participants and healthcare professionals. The model of...

KEY FINDING: Pressure injuries were a significant concern, discussed in at least one phone call with 43% of participants. Case-managers provided strategies to treat and prevent them.

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NeurologyBioinformaticsResearch Methodology & Design

Batch Bayesian optimization design for optimizing a neurostimulator

Biometrics, 2021 • June 1, 2021

The study proposes an adaptive method that tailors spinal cord stimulation devices to individual patient preferences. Batch Bayesian Optimization is used to balance exploration of the device configura...

KEY FINDING: Batch Bayesian optimization can be used to efficiently identify device configurations for long-term use with near-best patient preference.

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Spinal Cord InjuryNeurologyResearch Methodology & Design

The effects of mouse strain and age on a model of unilateral cervical contusion spinal cord injury

PLOS ONE, 2020 • June 15, 2020

This study profiles a clinically relevant model of unilateral cervical contusion injury in the mouse, demonstrating sustained behavioral deficits and exploring the effect of mouse strain and age on in...

KEY FINDING: Sustained behavioral deficits were observed in grip strength, cylinder reaching, horizontal ladderbeam, and CatWalk automated gait analysis tasks following unilateral cervical contusion SCI.

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Spinal Cord InjuryRehabilitationResearch Methodology & Design

An unusual mechanism of spinal cord injury due to active neck stretching and its functional implications

Clin Case Rep, 2020 • May 1, 2020

This case report describes an 18-year-old male who developed spinal cord injury without radiological abnormality (SCIWORA) following active neck stretching. The patient presented with weakness in all ...

KEY FINDING: Active neck stretching can lead to SCIWORA, even in the absence of vertebral column damage.

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Spinal Cord InjuryGastroenterologyResearch Methodology & Design

Colonic obstruction in a tetraplegic patient: a common symptom from an uncommon cause

Spinal Cord Series and Cases, 2020 • June 17, 2020

This case report highlights the difficulty in diagnosing acute abdominal conditions in patients with spinal cord injuries (SCI) due to altered sensation and multiple co-morbidities. A 57-year-old tetr...

KEY FINDING: The patient presented with nausea, vomiting, abdominal distension, and feeding intolerance, initially leading to a diagnosis of pseudo-gut obstruction due to severe hyponatremia.

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Spinal Cord InjuryNeurologyResearch Methodology & Design

Radial palsy in an individual with high-level chronic spinal cord injury

Spinal Cord Series and Cases, 2020 • June 14, 2020

This case report describes the first reported instance of acute compressive radial neuropathy in a tetraplegic patient. The patient, a 48-year-old man with a C6 AIS A SCI, experienced prolonged radial...

KEY FINDING: A patient with chronic SCI experienced acute compressive radial neuropathy due to prolonged compression from being stuck in his wheelchair.

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Spinal Cord InjuryUrologyResearch Methodology & Design

Correction: International spinal cord injury male sexual function and female sexual and reproductive function basic data sets—version 2.0

Spinal Cord Series and Cases, 2020 • January 1, 2020

This is a correction notice for an article published in Spinal Cord Series and Cases (2017) concerning international spinal cord injury data sets for sexual function. The correction pertains to an err...

KEY FINDING: The surname of author Giulio Del Popolo was incorrectly indexed in the original article.

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Spinal Cord InjuryResearch Methodology & Design

Behavioral testing in animal models of spinal cord injury

Exp Neurol, 2020 • November 1, 2020

This review provides guidance on using animal SCI models, sharing experiences, problems encountered, and conclusions drawn to aid researchers in preclinical studies. It covers injury models, behaviora...

KEY FINDING: Selecting the appropriate SCI model is crucial, involving consideration of injury type, location, and severity, aligning with the experimental question and outcome measures.

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