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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Research Methodology & Design Research

Browse the latest research summaries in the field of research methodology & design for spinal cord injury patients and caregivers.

Showing 371-380 of 702 results

Spinal Cord InjuryRehabilitationResearch Methodology & Design

Critical factors influencing the decision to enroll in a physical activity intervention among a predominant group of adults with spinal cord injury: a grounded theory study

Spinal Cord, 2021 • August 3, 2020

This study used a grounded theory approach to examine factors influencing the decision to enroll in physical activity research among adults with SCI. The research identified three core concerns: capab...

KEY FINDING: Adults with SCI consider their capability to participate based on scheduling, transportation, and secondary health conditions.

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SurgerySpinal DisordersResearch Methodology & Design

Delayed symptomatic spinal adhesive arachnoiditis after surgery for thoracolumbar flexion-distraction injury: A case report

International Journal of Surgery Case Reports, 2020 • August 25, 2020

This case report describes a 51-year-old man who developed delayed symptomatic spinal adhesive arachnoiditis with cauda equina syndrome three months after undergoing surgery for a traumatic thoracolum...

KEY FINDING: Delayed symptomatic spinal adhesive arachnoiditis can occur after surgery for thoracolumbar flexion-distraction injuries.

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Spinal Cord InjuryNeurologyResearch Methodology & Design

A prospective cohort study investigating contributors to mild cognitive impairment in adults with spinal cord injury: study protocol

BMC Neurology, 2020 • August 23, 2020

This study is a prospective cohort longitudinal study that will investigate factors contributing to cognitive impairment in individuals with SCI across a 12-month period with the incorporation of cont...

KEY FINDING: The study aims to determine the rate of MCI in adults with SCI, including MCI sub-types: single domain amnestic, multiple domain amnestic, single domain non-amnestic, and multiple domain non-amnestic.

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Spinal Cord InjuryResearch Methodology & DesignPublic Health

Etiology-specific variation in survival following non-traumatic spinal cord injury: a causal inference approach using data from a population-based cohort

Spinal Cord, 2021 • September 18, 2020

This population-based cohort study investigated the impact of different etiologies of non-traumatic spinal cord injury (NTSCI) on survival compared to traumatic spinal cord injury (TSCI). The study fo...

KEY FINDING: Mortality was elevated in all NTSCI etiological groups compared to TSCI, with malignant etiologies showing the highest hazard ratios.

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Spinal Cord InjuryRehabilitationResearch Methodology & Design

Participation instruments in persons with spinal cord injury: A narrative review

Medical Journal of the Islamic Republic of Iran, 2020 • June 23, 2020

The review examined six instruments used to assess participation in individuals with spinal cord injury, focusing on their measurement properties and applicability. The findings highlight the importan...

KEY FINDING: Six instruments were identified: I-APS, USER-P, WHODAS-II, IMPACT-S, IPA, and PM-PAC.

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Spinal Cord InjuryRegenerative MedicineResearch Methodology & Design

Progress in clinical trials of cell transplantation for the treatment of spinal cord injury: how many questions remain unanswered?

Neural Regeneration Research, 2021 • March 1, 2021

Cell transplantation holds promise for treating spinal cord injury (SCI) due to the inadequacies of current treatments. Stem cells, macrophages, and Schwann cells offer potential for nerve regeneratio...

KEY FINDING: Neural stem cell (NSC) transplantation has shown improvements in motor and sensory function in some patients with thoracic SCI, suggesting the potential of allogeneic NSCs.

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TraumaOrthopedicsResearch Methodology & Design

Six-year follow-up of a survivor of cervical spine fracture and dislocation with oesophageal perforation following long scarf syndrome - a case report and literature review

BMC Musculoskeletal Disorders, 2020 • September 28, 2020

This case report describes a rare instance of a 39-year-old female who survived a cervical spine fracture dislocation and oesophageal perforation following Long Scarf Syndrome. The patient was treated...

KEY FINDING: The patient survived a rare combination of cervical spine fracture dislocation and oesophageal perforation after Long Scarf Syndrome.

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Spinal Cord InjurySurgeryResearch Methodology & Design

“White Cord Syndrome” of Acute Tetraplegia after Posterior Cervical Decompression and Resulting Hypoxic Brain Injury

Asian Journal of Neurosurgery, 2020 • August 28, 2020

This case report describes a rare instance of White Cord Syndrome (WCS) following cervical decompression surgery, further complicated by a hypoxic brain injury (HBI). The patient, who initially presen...

KEY FINDING: The patient developed White Cord Syndrome (WCS) immediately after laminectomy, indicated by loss of motor-evoked potentials and postoperative imaging showing cord edema.

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NeurologyTraumaResearch Methodology & Design

Traumatic Brown-Séquard syndrome: modern reminder of a neurological injury

BMJ Case Rep, 2020 • October 17, 2020

Brown-Séquard syndrome (BSS) presents as an ipsilateral loss of motor function, proprioception and vibratory sensation accompanied by contralateral pain and temperature loss two to three levels below ...

KEY FINDING: The patient presented with left lower extremity weakness, decreased sensation to light touch, temperature, and vibration on the left side, and decreased sensitivity to touch and temperature on the right lower extremity, consistent with BSS.

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Spinal Cord InjuryBioinformaticsResearch Methodology & Design

Early CSF Biomarkers and Late Functional Outcomes in Spinal Cord Injury. A Pilot Study

International Journal of Molecular Sciences, 2020 • November 27, 2020

This pilot study explored the potential of early CSF biomarkers to predict functional outcomes in spinal cord injury patients. CSF samples were collected within 24 hours of injury, and levels of 38 bi...

KEY FINDING: MIP-1β, MIP-1α, MCP-1, IL-9 and IL-18 were positively associated with neurological level at discharge.

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