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  4. A Clinical Practice Guideline for Prevention, Diagnosis and Management of Intraoperative Spinal Cord Injury: Recommendations for Use of Intraoperative Neuromonitoring and for the Use of Preoperative and Intraoperative Protocols for Patients Undergoing Spine Surgery

A Clinical Practice Guideline for Prevention, Diagnosis and Management of Intraoperative Spinal Cord Injury: Recommendations for Use of Intraoperative Neuromonitoring and for the Use of Preoperative and Intraoperative Protocols for Patients Undergoing Spine Surgery

Global Spine Journal, 2024 · DOI: 10.1177/21925682231202343 · Published: March 1, 2024

Spinal Cord InjurySurgeryResearch Methodology & Design

Simple Explanation

This study developed guidelines for using intraoperative neuromonitoring (IONM) to detect spinal cord injuries during spine surgery. It identifies patients at higher risk and suggests protocols for prevention, diagnosis, and management. The guidelines recommend using IONM for high-risk patients undergoing spine surgery. They also suggest proactively identifying high-risk patients, having multi-disciplinary team discussions, and implementing an intraoperative protocol including IONM. The goal is to standardize the use of neuromonitoring and encourage surgeons to use it in an evidence-based manner to improve patient care and reduce the risk of complications.

Study Duration
Not specified
Participants
99,937 patients (across 164 studies)
Evidence Level
Clinical practice guideline (GRADE)

Key Findings

  • 1
    Intraoperative neurophysiologic monitoring is recommended for high-risk patients undergoing spine surgery, based on a review of 164 studies.
  • 2
    The sensitivity of MEP was found to be 90% (95% CI 86.1-92.9, Heterogeneity: I2 = 32%, τ2 = 1.91, P < .01), while the specificity was found to be 95.6%.
  • 3
    The GDG agreed that the following sub-entities of spinal pathologies are deemed high risk for the occurrence of an ISCI: (i) Rigid thoracic curve with high DAR; (ii) Revision surgery for congenital deformity with significant cord compression and myelopathy; (iii) extrinsic lesions with cord compression and myelopathy

Research Summary

These guidelines recommend intraoperative neurophysiologic monitoring for high-risk patients undergoing spine surgery to detect and manage intraoperative spinal cord injury. The guidelines suggest identifying high-risk patients, conducting multi-disciplinary team discussions, and implementing an intraoperative protocol including IONM. The aim is to promote the use of IONM, preoperative checklists, and evidence-based decision-making to improve patient outcomes and standardize care.

Practical Implications

Standardized IONM Use

The guidelines aim to standardize the use of intraoperative neuromonitoring (IONM) during spine surgery, promoting its use in an evidence-based manner.

Preoperative Risk Assessment

Encourages proactive identification of patients at high risk for intraoperative spinal cord injury (ISCI) to allow for tailored management strategies.

Multidisciplinary Collaboration

Promotes multidisciplinary team discussions for high-risk patients to optimize care pathways and treatment protocols.

Study Limitations

  • 1
    Low quality of evidence for some recommendations
  • 2
    Limited data on cost-effectiveness of IONM
  • 3
    Challenges in implementing guidelines in resource-poor areas

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