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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Pulmonology Research

Browse the latest research summaries in the field of pulmonology for spinal cord injury patients and caregivers.

Showing 21-30 of 155 results

Spinal Cord InjurySleep MedicinePulmonology

Intensive support does not improve positive-airway pressure use in spinal cord injury/disease: a randomized clinical trial

SLEEP, 2024 • February 29, 2024

The study aimed to evaluate the effectiveness of a comprehensive program (BEST) to improve PAP adherence for the treatment of SDB among individuals with SCI/D, compared to a non-directive educational ...

KEY FINDING: A 3-month supportive/behavioral program did not show significant benefit compared to education alone in increasing PAP use.

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Spinal Cord InjurySleep MedicinePulmonology

Not there yet; the challenge of treating sleep-disordered breathing in people living with spinal cord injury/disease

SLEEP, 2024 • March 7, 2024

This editorial discusses the challenges of treating sleep-disordered breathing (SDB) in people living with spinal cord injury/disease (SCI/D), focusing on a recent study by Badr et al. that investigat...

KEY FINDING: The Badr et al. study found no significant difference in PAP usage between the intervention and control groups, despite a comprehensive intervention aimed at improving adherence.

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Spinal Cord InjuryPulmonologyRehabilitation

Treadmill training improves lung function and inhibits alveolar cell apoptosis in spinal cord injured rats

Scientific Reports, 2024 • April 12, 2024

The study investigated the effects of treadmill training on lung function and alveolar cell apoptosis in rats with spinal cord injury (SCI). Treadmill training attenuated apoptosis in lung cells post-...

KEY FINDING: SCI increased apoptosis, activated the MAPK/Erk pathway, and impaired lung function in rats. Treadmill training, however, reduced alveolar cell apoptosis, suppressed the MAPK/Erk pathway, and improved lung function.

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Assistive TechnologyPulmonologyRehabilitation

Cardiopulmonary Response to Robot-Assisted Tilt Table With Regard to Its Components

Brain Neurorehabil, 2023 • March 31, 2023

This study investigated the effects of robot-assisted tilt table (RATT) exercise on cardiopulmonary function in healthy young adults. By manipulating the robot-assisted mode, tilt angle, and functiona...

KEY FINDING: The angle of the tilt table had a significant effect on cardiopulmonary function, with higher angles resulting in increased values for RPP, HR, and %HRmax when FES was switched off.

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Spinal Cord InjuryPulmonologyNeurology

Comparison of disc and wire electrodes to restore cough via lower thoracic spinal cord stimulation

The Journal of Spinal Cord Medicine, 2022 • January 1, 2022

This study compared disc (DE) and wire (WE) electrodes for restoring cough via lower thoracic spinal cord stimulation (SCS) in SCI subjects. Results showed no significant differences in expiratory mus...

KEY FINDING: Airway pressure (P) and peak airflow (F) achieved with disc electrodes (DE) and wire electrodes (WE) were not significantly different.

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Spinal Cord InjuryRegenerative MedicinePulmonology

Novel Regenerative Drug, SPG302 Promotes Functional Recovery of Diaphragm Muscle Activity After Cervical Spinal Cord Injury

J Physiol, 2023 • June 1, 2023

This study investigates the effects of SPG302, a novel regenerative drug, on diaphragm muscle (DIAm) function following cervical spinal cord hemisection (C2SH) in rats. The researchers assessed DIAm e...

KEY FINDING: C2SH causes marked EMG deficits across ventilatory behaviours

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Spinal Cord InjuryPulmonologyPain Management

The potential effects of untreated sleep-related breathing disorders on neuropathic pain, spasticity, and cardiovascular dysfunction following spinal cord injury: A cross-sectional prospective study protocol

PLoS ONE, 2023 • May 2, 2023

This cross-sectional prospective study will explore the previously understudied hypothesis that SRBDs are associated with increased neuropathic pain, spasticity, and cardiovascular autonomic dysfuncti...

KEY FINDING: Individuals with SCI and untreated SRBDs will develop more intense neuropathic pain.

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Spinal Cord InjuryPulmonologyRehabilitation

An automated pressure-swing absorption system to administer low oxygen therapy for persons with spinal cord injury

Exp Neurol, 2020 • November 1, 2020

This study evaluated a novel 'automated' system for delivering acute intermittent hypoxia (AIH) compared to a 'manual' system, focusing on improvements in accuracy, reliability, and safety for individ...

KEY FINDING: The 'automated' delivery system demonstrated a goodness-of-fit of 98.1% to the 'ideal' AIH protocol, compared to 34.8% for the 'manual' system, indicating improved accuracy in dose timing.

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PulmonologyOrthopedicsSpinal Disorders

Report on the clinical outcomes of using postural drainage with intervertebral space as the main focus for managing thoracolumbar tuberculosis

Medicine, 2025 • January 1, 2025

This clinical case report assesses the outcomes of postural drainage targeting the intervertebral space, combined with chemotherapy, for treating thoracolumbar tuberculosis. Eight cases of thoracolum...

KEY FINDING: Postural drainage focusing on the intervertebral space, combined with chemotherapy, led to significant improvements in erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), Visual Analogue Scale (VAS) score, American Spinal Cord Injury Association (ASIA) score, and Oswestry functional index.

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Spinal Cord InjuryPulmonologyRehabilitation

Clinical introduction and benefits of non-invasive ventilation for above C3 cervical spinal cord injury

The Journal of Spinal Cord Medicine, 2021 • January 1, 2021

This retrospective study investigated the clinical introduction and benefits of non-invasive ventilation (NIV) for patients with high-level cervical spinal cord injuries (CSCI). The study aimed to det...

KEY FINDING: Switching to NIV was more successful when implemented within one year of the spinal cord injury.

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