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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Physiology Research

Browse the latest research summaries in the field of physiology for spinal cord injury patients and caregivers.

Showing 81-90 of 321 results

Spinal Cord InjuryEndocrinologyPhysiology

Impaired Glucose Tolerance and Visceral Adipose Tissue Thickness among Lean and Non-Lean People with and without Spinal Cord Injury

J. Funct. Morphol. Kinesiol., 2023 • August 21, 2023

The study compared glucose tolerance biomarkers among people with and without SCI, finding that individuals with SCI are more glucose intolerant compared to people without SCI. It also compared glucos...

KEY FINDING: Glucose levels were significantly higher in individuals with SCI compared to those without SCI at 60 and 120 minutes after an oral glucose tolerance test (OGTT).

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Spinal Cord InjuryPhysiologyNeurology

Characterizing neurological status in individuals with tetraplegia using transcutaneous spinal stimulation

Scientific Reports, 2023 • December 6, 2023

This study examined upper limb motor pool recruitment patterns using transcutaneous spinal stimulation (TSS) in individuals with tetraplegia following cervical spinal cord injury (SCI). TSS was delive...

KEY FINDING: Responses in muscles below the injury were less sensitive to TSS compared to those above the lesion.

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Spinal Cord InjuryPhysiologyRehabilitation

Secondary Sarcopenia and Spinal Cord Injury: Clinical Associations and Health Outcomes

J. Clin. Med., 2024 • February 2, 2024

This study investigated the prevalence and associations of sarcopenia in patients with spinal cord injury (SCI). The research found significant associations between sarcopenia and gender, age, and the...

KEY FINDING: Women with SCI are more likely to develop sarcopenia than men.

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Spinal Cord InjuryPhysiologyPublic Health

Effect of body mass index on survival after spinal cord injury

Frontiers in Neurology, 2024 • January 26, 2024

This study investigated the impact of body mass index (BMI) at admission on mortality rates in patients with traumatic spinal cord injury (SCI) over a period of up to 7.7 years. The study found that b...

KEY FINDING: Underweight individuals (BMI < 17.5 kg/m²) had a significantly elevated risk of mortality (HR 5.55, 95% CI 2.34–13.17, p < 0.001) compared to the mid-range BMI group (17.5–30.5 kg/m²).

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Spinal Cord InjuryPhysiologyRehabilitation

Safety of mapping the motor networks in the spinal cord using penetrating microelectrodes in Yucatan minipigs

J Neurosurg Spine, 2024 • May 10, 2024

This study assessed the safety of mapping spinal cord locomotor networks using penetrating stimulation microelectrodes in Yucatan minipigs (YMPs). The researchers found that mapping spinal locomotor n...

KEY FINDING: All YMPs showed transient deficits in hindlimb function postoperatively.

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Spinal Cord InjuryPhysiologyRehabilitation

Optimizing assessment of low frequency H-reflex depression in persons with spinal cord injury

PLOS ONE, 2024 • May 14, 2024

This study compared different methods of assessing low-frequency depression (LFD) of H-reflexes in individuals with incomplete spinal cord injury (SCI). The goal was to identify a shorter, more effici...

KEY FINDING: The amount of depression produced by paired-pulse depression (PPD) was less than an 11-pulse train.

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Spinal Cord InjuryPhysiologyNeurology

Why do different people with Spinal Cord Injury have differing severity of symptoms with Autonomic Dysreflexia? Exploring relationships of vascular alpha-1 adrenoreceptor and baroreflex sensitivity after SCI

medRxiv preprint, 2024 • May 3, 2024

This study investigated the relationship between autonomic dysreflexia (AD) symptoms, baroreflex sensitivity, and vascular responsiveness in individuals with spinal cord injury (SCI). The researchers ...

KEY FINDING: Individuals with SCI exhibited significantly lower baroreflex sensitivity compared to controls, indicating a reduced ability to regulate blood pressure.

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Spinal Cord InjuryPhysiologyNeurology

Sex hormone supplementation improves breathing and restores respiratory neuroplasticity following C2 hemisection in rats

Frontiers in Physiology, 2024 • May 13, 2024

The study investigated the impact of sex hormone supplementation on respiratory function and neuroplasticity following cervical spinal cord injury (SCI) in rats. The primary findings indicate that C2 ...

KEY FINDING: C2 hemisection significantly reduced serum testosterone levels for at least 2 weeks post-injury.

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PhysiologyNeurologyRehabilitation

Effect of muscle length on maximum evoked torque, discomfort, contraction fatigue, and strength adaptations during electrical stimulation in adult populations: A systematic review

PLoS ONE, 2024 • June 10, 2024

This systematic review investigated the impact of muscle length on neuromuscular electrical stimulation (NMES) outcomes, including evoked torque, discomfort, contraction fatigue, and strength adaptati...

KEY FINDING: Optimal quadriceps muscle length (50˚ - 70˚ of knee flexion) results in greater evoked torque during nerve stimulation compared to very short, short, and long muscle lengths.

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PhysiologyNeurologyResearch Methodology & Design

Electrophysiology Methods for Assessing of Neurodegenerative and Post-Traumatic Processes as Applied to Translational Research

Life, 2024 • June 7, 2024

Electrophysiological studies, including EEG and EMG, are crucial for assessing brain and spinal cord function, neurodegeneration, and the effectiveness of therapies. These methods can be applied in bo...

KEY FINDING: EEG data in animals and humans are practically comparable under normal conditions, with some differences related to anatomical features and behavioral patterns.

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