Browse the latest research summaries in the field of physiology for spinal cord injury patients and caregivers.
Showing 71-80 of 321 results
ACS Omega, 2018 • November 2, 2018
The study demonstrates a method for fabricating aggregated L-cysteine-protected copper nanoclusters into 3D nanomaterials with a mesoporous sphere structure using Ce3+ as a crosslinking agent. The int...
KEY FINDING: Ce3+ ions can be used to crosslink and rearrange L-cysteine-protected copper nanoclusters into ordered mesoporous spheres.
Biomedicines, 2023 • September 22, 2023
This study aimed to investigate the relationships between the different levels and degrees of incomplete spinal cord injury (iSCI) evaluated with magnetic resonance imaging (MRI) and the results of no...
KEY FINDING: The study revealed consistent positive correlations in iSCI patients between the bilateral decrease of the spinal half injury MRI scores and a decrease of the transcranially-evoked MEP amplitudes.
Scientific Reports, 2022 • July 15, 2022
This study aimed to refine the definition of optimal peripheral nerve stimulation (PNS) intensity in paired associative stimulation (PAS) protocols using high-frequency PNS, called “high-PAS”. Two exp...
KEY FINDING: PAS with PNS intensity defined as the level required to achieve 7/10 F-response persistence did not produce significant MEP potentiation.
Spinal Cord, 2018 • June 1, 2018
This study characterized hindlimb EMG patterns in rats with SCI in response to muscle stretch, identifying clonic-like, air-stepping, and spasm responses, which are similar to those seen in humans. Th...
KEY FINDING: Three main EMG patterns in response to stretch were identified: clonic-like, air-stepping, and spasms.
Neuromodulation, 2023 • July 1, 2023
This study investigates the spatiotemporal distribution of spinal ECAPs during SCS in sheep, examining how these ECAPs relate to lower extremity motor responses. The researchers found that spinal ECAP...
KEY FINDING: Distinct regions of lateral stimulation resulted in simultaneously increased ECAP and EMG responses compared to stimulation at adjacent lateral contacts.
Frontiers in Neurology, 2023 • June 2, 2023
This study examined the changes in corticospinal excitability (CSE) of the primary motor cortex (M1) hand area after spinal cord injury (SCI) and its correlation with motor function and activities of ...
KEY FINDING: The CSE of the dominant hemisphere M1 hand area decreased in SCI patients.
bioRxiv preprint, 2023 • July 3, 2023
The study investigates the effects of Dynamic Stimulation (DS) on corticospinal motor responses using a corticospinal platform in rats. The platform allows for selective cortical stimulation and simul...
KEY FINDING: Dynamic Stimulation (DS) selectively increases the excitability of spinal interneurons that first process corticospinal input, without altering the magnitude of commands from the motor cortex.
Front. Rehabil. Sci., 2023 • July 26, 2023
This study evaluated the acute cardiovascular effects of a 20-min session of high PAS on 17 healthy individuals by measuring heart rate variability (HRV). The results showed a transient increase in pa...
KEY FINDING: A significant decrease in low-frequency (LF) power and low-frequency to high-frequency (HF) ratio was observed during stimulation, indicating increased parasympathetic activity.
FUNCTION, 2023 • June 13, 2023
The study investigated the influence of genetics, age, and sex on respiratory motor plasticity induced by AIHH in healthy adults. Results showed that the APOE4 genotype, sex, and age are significant d...
KEY FINDING: Individuals heterozygous for APOE4 showed lower AIHH-induced changes in diaphragm MEP amplitudes.
bioRxiv preprint, 2023 • August 4, 2023
This study investigates the role of Nox4 in reduced muscle specific force after spinal cord injury (SCI) using a conditional knockout mouse model. The results suggest a link between Nox4 expression in...
KEY FINDING: Peak twitch force in control mice after SCI was reduced by 42% compared to sham-operated controls.