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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Physiology Research

Browse the latest research summaries in the field of physiology for spinal cord injury patients and caregivers.

Showing 91-100 of 321 results

PhysiologyNeurologyPediatrics

Muscle Mass as a Biomarker for Health Status and Function in Pediatric Individuals with Neuromuscular Disabilities: A Systematic Review

Children, 2024 • July 3, 2024

This systematic review investigates the relationship between muscle mass and health outcomes in children with neuromuscular disorders. The review included 32 studies, demonstrating relationships betwe...

KEY FINDING: There is a recognized relationship between muscle mass and important health outcomes in children.

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Spinal Cord InjuryParticipationPhysiology

Association Between Sarcopenic Obesity and Activities of Daily Living in Individuals with Spinal Cord Injury

J. Clin. Med., 2024 • November 22, 2024

This study investigated the relationship between sarcopenic obesity and ADL in individuals with chronic SCI, revealing that decreased SMI and increased %BF were independently associated with reduced A...

KEY FINDING: Participants with sarcopenic obesity had significantly lower FIM motor scores than those without the condition (54 vs. 69 points, p = 0.006).

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Spinal Cord InjuryPhysiologyMedical Imaging

Ultrasound Evaluation of Upper Limb Sublesional Muscle Morphology in Cervical Spinal Cord Injury

Muscle & Nerve, 2025 • January 12, 2025

This study evaluated muscle morphology changes in upper limb muscles of individuals with cervical spinal cord injury (cSCI) using ultrasound and compared them to healthy controls (HC). The results sho...

KEY FINDING: Forearm and hand muscle size were significantly lower (15%-41%) in individuals with cSCI compared to healthy controls.

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Spinal Cord InjuryPhysiologyNeurology

Electrical stimulation of the sciatic nerve restores inspiratory diaphragm function in mice after spinal cord injury

Frontiers in Neural Circuits, 2025 • January 22, 2025

This study investigates the effects of electrical stimulation of the sciatic nerve on diaphragm activity in healthy and spinal cord injured mice. The study found that electrical stimulation can increa...

KEY FINDING: Electrical stimulation of the sciatic nerve can increase diaphragm activity in uninjured mice, confirming previous findings in other species.

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PhysiologyOrthopedicsRehabilitation

Neurophysiology of ACL Injury

Orthopedic Reviews, 2025 • February 18, 2025

ACL injuries disrupt neural connectivity, sensory processing, and motor control, affecting the CNS and necessitating comprehensive rehabilitation. Neuroplastic therapy addresses neuromuscular and neur...

KEY FINDING: ACL injuries disrupt the sensorimotor control of the knee, affecting proprioceptive accuracy, muscular reflexes, and motor control strategies.

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Spinal Cord InjuryPhysiologyPublic Health

The impact of body mass index on one-year mortality after spinal cord injury

The Journal of Spinal Cord Medicine, 2021 • July 1, 2021

This study investigated the impact of BMI on one-year mortality among individuals who survived the first 90 days after SCI. The study found that obese individuals had a significantly higher mortality ...

KEY FINDING: Obese individuals with SCI had a 51% higher mortality risk within the first year compared to those with normal weight, after adjusting for demographic and injury-related factors.

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Spinal Cord InjuryPhysiologyRehabilitation

Effects of arm cranking exercise on muscle oxygenation between active and inactive muscles in people with spinal cord injury

The Journal of Spinal Cord Medicine, 2021 • January 1, 2021

The study examined the effects of incremental arm-cranking exercise on tissue oxygen saturation (StO2) in active (biceps brachii) and inactive (vastus lateralis) muscles among individuals with complet...

KEY FINDING: Muscle oxygenation in the lower limbs of complete SCI participants remained unchanged during arm-crank exercise, while it decreased in incomplete SCI and able-bodied participants.

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PhysiologyNeurologySpinal Disorders

Diagnostic Role of Flexion-extension Central Motor Conduction Time in Cervical Spondylotic Myelopathy

Spine, 2021 • November 1, 2021

The study evaluated the diagnostic usefulness of flexion-extension CMCT in patients with CSM, comparing CMCT values across different neck positions and MRI findings. CMCT was significantly slower in n...

KEY FINDING: CMCT was significantly delayed in both neck flexion and extension compared to the neutral neck position.

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Spinal Cord InjuryPhysiologyRehabilitation

Associations between left ventricular structure and function with cardiorespiratory fitness and body composition in individuals with cervical and upper thoracic spinal cord injury

Spinal Cord, 2021 • December 7, 2020

This study examined the associations between resting echocardiographic LV structure and function parameters and CRF, as well as exploring the associations between LVM and DXA-obtained body composition...

KEY FINDING: Resting left ventricular parameters are not associated with peak oxygen consumption (V̇O2peak) in individuals with cervical and upper-thoracic SCI.

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Spinal Cord InjuryUrologyPhysiology

The Video-Urodynamic and Electrophysiological Characteristics in Patients With Traumatic Spinal Cord Injury

International Neurourology Journal, 2021 • December 31, 2021

This study aimed to determine the characteristics of detrusor behavior, urodynamic examination findings, and neurophysiological tests in patients with traumatic SCI. The results showed a correlation b...

KEY FINDING: A significant correlation was found between the level of SCI and video-urodynamic findings, but clinical examination cannot accurately predict bladder function.

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