Browse the latest research summaries in the field of physiology for spinal cord injury patients and caregivers.
Showing 11-20 of 321 results
Eur J Neurol, 2025 • January 1, 2025
CHEPs revealed distinct patterns of spinal cord impairment independent of structural T2-positive lesions, which were associated with measures of cord motion. CHEPs thus provide valuable complementary...
KEY FINDING: Abnormal CHEPs were present in T2-positive DCM (C6:41%; C8:32%; T4:24%) and T2-negative DCM (C6:35%; C8:54%; T4:26%).
Scientific Reports, 2025 • January 1, 2025
This study used CT scans of 160 Emirati patients to determine the optimal screw dimensions, entry points, bony corridors, and screw trajectories for C1 lateral mass screw placement. The research ident...
KEY FINDING: The study found that a screw entry at the center of the lateral mass, below its junction with the posterior arch, allowed straight screws of lengths 20 mm and 19.5 mm in Emirati males and females, respectively.
Cureus, 2024 • December 18, 2024
The case report highlights a rare anatomical variation where the vertebral artery originates from the internal carotid artery, potentially leading to posterior circulation neurological deficits if the...
KEY FINDING: A dominant right vertebral artery was found to originate from the right internal carotid artery in a 76-year-old female.
Scientific Reports, 2025 • January 14, 2025
This study investigates the therapeutic effect of NaHS on neuropathic pain using the spared nerve injury (SNI) model in mice, focusing on astrocytes and glutamate. The findings reveal that NaHS enhanc...
KEY FINDING: SNI induces chronic pain and depressive-like behaviors in mice, evidenced by decreased mechanical pain threshold, thermal pain latency, and reduced exploratory behavior.
Journal of Pain Research, 2025 • January 21, 2025
The study comprehensively analyzed methodology and technical challenges and pitfalls encountered during the development and implementation of this model. We presented a reliable electrophysiological p...
KEY FINDING: SNI enhanced the C component of eLFPs in bilateral cortexes elicited by stimulating the contralateral but not the ipsilateral lateral aspect of the hind paw.
Materials Today Bio, 2022 • September 2, 2022
The review summarizes the progress made in the applications of GSNO in anti-infective biomaterials. It mainly includes the biological properties of GSNO and its application in biomaterials and provid...
KEY FINDING: GSNO possesses antibacterial activity influenced by factors like bacterial strain, dose, treatment duration, and NO release kinetics. Studies have evaluated GSNO's antibacterial properties in pulmonary, cutaneous, and other infections.
PLoS ONE, 2022 • October 5, 2022
This study compared four recompression treatment tables (TT6, TT6A-air, TT6A-nitrox, TT6A-heliox) for neurologic decompression illness (DCI) in a swine model. The primary outcome was the mean number o...
KEY FINDING: No significant differences were found in functional neurologic outcomes among the four treatment groups (TT6, TT6A-air, TT6A-nitrox, and TT6A-heliox) or between the two treatment profiles (TT6 and TT6A).
CNS Neurosci Ther, 2023 • January 1, 2023
This study investigates the modulation of glycans in glial cells during neuroinflammation associated with spinal cord injury (SCI) using a mixed glial culture model. The researchers used lectin microa...
KEY FINDING: Differential glycosylation occurs in glial cells during the transition from acute to chronic inflammation in a mixed glial culture model induced by cytokines.
Int. J. Environ. Res. Public Health, 2023 • February 19, 2023
This retrospective study evaluated the role of TMS and SSEP in the diagnosis and post-surgical follow-up of DCM patients. Twenty-four patients undergoing surgical decompression were assessed using neu...
KEY FINDING: Post-operative TMS and SSEP results did not correlate with clinical outcomes at six months.
Nature Communications, 2023 • May 26, 2023
This study uses spatial metabolomics to understand the biology of pulmonary fibrosis (PF) by identifying a potential role for glycogen utilization during fibrosis disease progression. The researchers ...
KEY FINDING: High-dimensionality reduction and spatial clustering (HDR-SC) of MALDI-MSI datasets can accurately identify tissue microanatomy in both healthy and diseased lung tissues.