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  4. The Role of Magnetic Transcranial Stimulation in the Diagnosis and Post-Surgical Follow-Up of Cervical Spondylotic Myelopathy

The Role of Magnetic Transcranial Stimulation in the Diagnosis and Post-Surgical Follow-Up of Cervical Spondylotic Myelopathy

Int. J. Environ. Res. Public Health, 2023 · DOI: 10.3390/ijerph20043690 · Published: February 19, 2023

PhysiologyNeurologySurgery

Simple Explanation

Degenerative cervical myelopathy (DCM) involves spinal cord damage from compression in the cervical spine, often requiring surgery. While MRI confirms the diagnosis, it lacks functional information. Neurophysiological tests like SSEPs and TMS can assess spinal cord function, aiding diagnosis and post-surgery monitoring. This study examines 24 DCM patients who had surgery and underwent neurophysiological testing before and after the procedure.

Study Duration
Between 2018 and 2020
Participants
24 patients with DCM and surgical decompression
Evidence Level
Not specified

Key Findings

  • 1
    Post-operative TMS and SSEP results did not correlate with clinical outcomes at six months.
  • 2
    Improvement in central conduction times (CMCTs) after surgery was only observed in patients with severe pre-surgical motor impairment on TMS.
  • 3
    CMCT and SSEP were more related to clinical outcomes one year after surgery and were very useful in diagnosing.

Research Summary

This retrospective study evaluated the role of TMS and SSEP in the diagnosis and post-surgical follow-up of DCM patients. Twenty-four patients undergoing surgical decompression were assessed using neurophysiological tests before and after surgery. The study found that post-operative TMS and SSEP did not correlate with clinical outcomes at six months. However, CMCT improvement was noted in patients with severe pre-surgical motor impairment. CMCT and SSEP were found to be more related to clinical outcomes one year after the surgical procedure and were very useful in diagnosing.

Practical Implications

Diagnostic Aid

Neurophysiological tests can support clinical diagnosis, especially when MRI findings are normal but symptoms suggest DCM.

Surgical Timing

Early surgical intervention may be considered based on neurophysiological evidence of spinal cord dysfunction, potentially preventing long-term neurological sequelae.

Post-operative Assessment

Clinical follow-up might be sufficient for assessing post-operative outcomes, while neurophysiological tests, if used, should be assessed one year after surgery.

Study Limitations

  • 1
    Small number of patients recruited
  • 2
    Loss of some patients due to neurophysiological test intolerance
  • 3
    Clinical evaluation was performed only at six months

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