Browse the latest research summaries in the field of physiology for spinal cord injury patients and caregivers.
Showing 21-30 of 321 results
The Journal of Neuroscience, 2023 • August 2, 2023
This study investigates the mechanisms underlying decreased PVIN output in neuropathic pain using computational and experimental approaches. The study identifies a calcium-dependent mechanism involvin...
KEY FINDING: Nerve injury induces a change in PVIN firing patterns from tonic to adaptive in male mice.
Neural Regen Res, 2024 • May 31, 2023
This review introduces artificial hibernation technologies, including mild hypothermia technology, hibernation inducers, and hibernation-related central neuromodulation technology. These studies show ...
KEY FINDING: Artificial hibernation technologies have therapeutic significance on nerve injury after spinal cord injury through inflammatory inhibition, immunosuppression, oxidative defense, and possible central protection.
Pflügers Archiv - European Journal of Physiology, 2023 • August 25, 2023
This study assessed the reliability of electrical stimulation to measure detection and pain thresholds in the skin and muscles of the lower back, comparing these measurements to established quantitati...
KEY FINDING: Excellent intra-session reliability was observed for cutaneous and intramuscular electrical stimulations.
Scientific Reports, 2023 • August 11, 2023
This study examined the morphological differences in phrenic motoneurons between control rats that underwent a C2HS, rats that underwent both a C2HS and a 3-week hypercapnic challenge, rats that under...
KEY FINDING: The average diameter, cross-sectional area, and somal surface area of stained phrenic motoneurons were significantly smaller in the control group compared to the other groups.
J. Clin. Med., 2023 • August 10, 2023
This retrospective study reviews ten syringomyelia surgeries using intraoperative neurophysiological monitoring (IONM) to prevent spinal cord damage. The study found that multimodal IONM, including ME...
KEY FINDING: Multimodal IONM, including MEPs, SEPs, EMG, and mapping techniques, is feasible and reliable in syringomyelia surgery.
FUNCTION, 2023 • August 8, 2023
The study demonstrates that the magnitude and mechanism of phrenic long-term facilitation (pLTF) are profoundly affected by the daily rest/active phase and the duration of hypoxic episodes within an a...
KEY FINDING: Basal spinal adenosine levels are significantly higher during the active phase compared to the rest phase in rats.
Nature Human Behaviour, 2024 • October 30, 2023
This study demonstrates that individuals can learn to control their pupil size using biofeedback, which in turn influences brain activity in arousal-related areas. The research shows that self-regulat...
KEY FINDING: Pupil-based biofeedback enables participants to gain volitional control of their pupil size.
Respir Physiol Neurobiol, 2024 • February 1, 2024
This study investigates the effects of closed-loop epidural stimulation (CL-ES) on restoring diaphragm activity after acute C2 hemisection in anesthetized rats. The results demonstrate that CL-ES can ...
KEY FINDING: CL-ES recovers spontaneous EMG activity acutely after injury.
Cureus, 2023 • November 27, 2023
This retrospective study evaluated the surgical management of degenerative cervical myelopathy (DCM) in Northern Ireland over three years, with a one-year follow-up, using data from the Fracture Outco...
KEY FINDING: The mJOA score tends to improve after surgery for the majority of patients, particularly at six months, which is consistent with the literature.
Mædica - a Journal of Clinical Medicine, 2023 • October 20, 2023
This review comprehensively examines atlas stenosis, focusing on its anatomical basis, clinical significance, diagnosis, and treatment. It emphasizes the role of congenital abnormalities and acquired ...
KEY FINDING: Congenital atlas anomalies result from embryogenesis failures, impacting the development of the anterior tubercle, anterior arch, posterior arch, and posterior tubercle.