Physiology Research

KEY FINDING: In patients with motor complete SCI, a positive correlation was found between hip adductor muscle spasticity and trunk, android, and gynoid fat-free mass percentages.

KEY FINDING: The phrenic nerve, which controls the diaphragm, is not uniform; the right and left nerves have differing compositions, with the right nerve containing more total axons.

KEY FINDING: Unilateral diaphragmatic afferents reflexly inhibit motor activity to the ipsilateral EI muscles during HF-SCS.

KEY FINDING: 73.5% of patients were classified as obese upon admission, half were at risk of malnutrition, and 29.4% were compatible with cachexia.

KEY FINDING: Both higher %FM and lower %LM were associated with markers of inflammation (hs-CRP) and metabolic syndrome.

KEY FINDING: Both the soleus H and soleus PRM reflex amplitudes were higher relative to the non-injured group and modulated less during the step cycle in SCI subjects.

KEY FINDING: Adults with complete cervical SCI tend to have absent diurnal melatonin rhythms compared to healthy controls and individuals with thoracolumbar SCI below T3.

KEY FINDING: Individuals with tetraplegia had significantly higher total caloric, fat, and protein intake when adjusted for body weight compared to those with paraplegia.

KEY FINDING: Glucose, lactic acid, and pyruvic acid levels are reduced in paralyzed skeletal muscle at 7 days post-SCI, indicating a disruption in glucose uptake.

KEY FINDING: The combination of low-dose TRT and RT resulted in significant hypertrophy of the glutei muscles compared to TRT alone.