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  4. Neurophysiology of ACL Injury

Neurophysiology of ACL Injury

Orthopedic Reviews, 2025 · DOI: 10.52965/001c.129173 · Published: February 18, 2025

PhysiologyOrthopedicsRehabilitation

Simple Explanation

ACL injury involves profound alterations in the central and peripheral nervous systems, impacting sensorimotor integration and neuromuscular control. Neuroplastic therapy employs tools like external focus strategies, stroboscopic glasses, smartboards, and virtual reality to restore and enhance neural connectivity, sensory integration, and motor coordination. This therapeutic approach integrates visual-cognitive, proprioceptive, and reflexive controls to accelerate recovery, optimize performance, and reduce reinjury risk.

Study Duration
Not specified
Participants
Not specified
Evidence Level
Not specified

Key Findings

  • 1
    ACL injuries disrupt the sensorimotor control of the knee, affecting proprioceptive accuracy, muscular reflexes, and motor control strategies.
  • 2
    Brain regions undergo significant neurophysiological changes, affecting sensory, motor processing, and neuromuscular coordination.
  • 3
    Acute inflammation after ACL injury impacts cellular behavior and subsequent neurophysiological responses, driving arthrogenic muscle inhibition (AMI).

Research Summary

ACL injuries disrupt neural connectivity, sensory processing, and motor control, affecting the CNS and necessitating comprehensive rehabilitation. Neuroplastic therapy addresses neuromuscular and neurocognitive deficits with targeted exercises challenging visual, proprioceptive, and reflexive controls. This approach enhances neural plasticity, motor learning, restores dynamic stability, and prepares athletes for unpredictable sports environments, reducing reinjury risks.

Practical Implications

Enhanced Rehabilitation Strategies

Neuroplastic therapies can be integrated into rehabilitation programs to improve neural connectivity and motor coordination.

Improved Performance

Optimizing sensory integration and motor control can lead to enhanced athletic performance and reduced injury risk.

Personalized Treatment Plans

Understanding neurophysiological mechanisms allows for tailored interventions addressing individual deficits in sensorimotor control.

Study Limitations

  • 1
    Lack of specific protocols for neuroplastic rehabilitation.
  • 2
    Limited longitudinal studies assessing long-term neurophysiological changes.
  • 3
    Individual variability in response to neuroplastic interventions.

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