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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Pain Management Research

Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.

Showing 521-530 of 682 results

Spinal Cord InjuryPharmacologyPain Management

A Systematic Review of Pharmacological Treatments of Pain Following Spinal Cord Injury

Arch Phys Med Rehabil, 2010 • May 1, 2010

This review supports the use of anticonvulsants such as gabapentin or pregabalin for post-SCI neuropathic pain. Tricyclic antidepressants were supported by limited evidence in those patients with supe...

KEY FINDING: Gabapentin and pregabalin, anticonvulsant medications, have strong evidence for effectiveness in treating neuropathic pain post-SCI.

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Spinal Cord InjuryNeurologyPain Management

A multidisciplinary cognitive behavioural programme for coping with chronic neuropathic pain following spinal cord injury: the protocol of the CONECSI trial

BMC Neurology, 2010 • October 20, 2010

The CONECSI trial evaluates a multidisciplinary cognitive behavioural programme for chronic neuropathic spinal cord injury pain (CNSCIP). The intervention aims to decrease pain intensity and related d...

KEY FINDING: The primary aim of the CONECSI trial is to evaluate the effects of a multidisciplinary cognitive behavioural treatment programme on pain intensity and pain-related disability

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Mental HealthPain ManagementRehabilitation

Psychosocial Factors and Adjustment to Chronic Pain in Persons With Physical Disabilities: A Systematic Review

Arch Phys Med Rehabil, 2011 • January 1, 2011

This systematic review investigated the associations between psychosocial factors and adjustment to chronic pain in individuals with physical disabilities, focusing on spinal cord injury (SCI), acquir...

KEY FINDING: Psychosocial factors, including catastrophizing, coping styles, and social support, are significantly linked to pain and dysfunction across various disability groups.

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Spinal Cord InjuryPain ManagementRehabilitation

Efficacy of cranial electrotherapy stimulation for neuropathic pain following spinal cord injury: a multi-site randomized controlled trial with a secondary 6-month open-label phase

The Journal of Spinal Cord Medicine, 2011 • January 1, 2011

This multi-site study evaluated the efficacy of cranial electrotherapy stimulation (CES) for neuropathic pain in individuals with spinal cord injury (SCI). The results indicated that active CES provid...

KEY FINDING: The active CES group reported a significantly greater average decrease in pain during daily treatments compared to the sham group.

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Spinal Cord InjuryNeurologyPain Management

Intra-spinal microstimulation may alleviate chronic pain after spinal cord injury

Med Hypotheses, 2017 • July 1, 2017

Chronic pain after spinal cord injury (SCI) is a debilitating condition often resistant to current treatments. The authors hypothesize that intraspinal microstimulation (ISMS) may alleviate SCI pain b...

KEY FINDING: ISMS may induce frequency-dependent conduction block on axons of afferent sensory neurons, in the spinothalamic tract and Lissauer’s tract.

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NeurologyPain ManagementRehabilitation

Swimming Training Reduces Neuroma Pain by Regulating Neurotrophins

Med. Sci. Sports Exerc., 2018 • January 1, 2018

This study investigated the effects of long-term swimming exercise on neuroma pain and neurotrophin expression in a rat model of tibial neuroma transposition (TNT). The results showed that swimming ex...

KEY FINDING: Swimming exercise alleviated neuroma pain and mechanical allodynia in rats with tibial neuroma transposition (TNT).

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Spinal Cord InjuryPain Management

Effect of Patient Education on Reducing Medication in Spinal Cord Injury Patients With Neuropathic Pain

Annals of Rehabilitation Medicine, 2017 • July 1, 2017

This prospective study evaluated the impact of a 6-week educational pain management program on reducing medication use in 109 spinal cord injury (SCI) patients with neuropathic pain. The study found t...

KEY FINDING: The number of patients taking more than two types of pain medication decreased from 72.5% to 33.0% after the educational program.

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Spinal Cord InjuryCardiovascular SciencePain Management

Neck-to-shoulder pain as an unusual presentation of pulmonary embolism in a patient with cervical spinal cord injury: A case report

Medicine, 2017 • October 20, 2017

This case report describes a patient with cervical spinal cord injury who presented with neck-to-shoulder pain, which was later diagnosed as pulmonary embolism. The patient's pain was initially though...

KEY FINDING: Neck-to-shoulder pain can be an atypical symptom of pulmonary embolism, especially in patients with cervical spinal cord injury.

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Pain ManagementGeneticsRehabilitation

IL1β inhibition contributes to the anti-nociceptive effects of voluntary exercise on ischemia/reperfusion-induced hypersensitivity

Pain, 2018 • February 1, 2018

This study demonstrates that voluntary exercise prior to I/R injury blocks the increase in muscle IL1β and subsequent pain-related behaviors, suggesting a protective effect against ischemic myalgia. T...

KEY FINDING: Voluntary exercise prior to ischemia/reperfusion injury (I/R) prevents injury-induced muscle IL1β upregulation and subsequent pain-related behaviors.

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ImmunologyPain ManagementRehabilitation

IL-4 mediates the analgesia produced by low-intensity exercise in mice with neuropathic pain

Pain, 2018 • March 1, 2018

This study investigates the mechanisms by which low-intensity exercise reduces neuropathic pain in mice after peripheral nerve injury (PNI). The researchers hypothesized that exercise restores anti-in...

KEY FINDING: Low-intensity treadmill exercise improved neuropathic pain behaviors in mice, including mechanical hyperalgesia, escape/avoidance behavior, and spontaneous locomotor activity.

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