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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Pain Management Research

Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.

Showing 381-390 of 682 results

NeurologyPain ManagementGastroenterology

Treatment of Chronic Abdominal Pain With 10-kHz Spinal Cord Stimulation: Safety and Efficacy Results From a 12-Month Prospective, Multicenter, Feasibility Study

Clinical and Translational Gastroenterology, 2020 • February 7, 2020

This prospective, single-arm study was designed to evaluate the safety and efficacy of 10-kHz spinal cord stimulation (SCS) in patients with intractable CAP over a 12-month follow-up period. After 12 ...

KEY FINDING: After 12 months of treatment with 10-kHz SCS, 78.3% of subjects were responders (pain relief of ‡50%).

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NeurologyPain Management

10-kHz Spinal Cord Stimulation for Chronic Postsurgical Pain: Results From a 12-Month Prospective, Multicenter Study

Pain Practice, 2020 • January 1, 2020

This prospective, multicenter study evaluated the effectiveness of 10-kHz SCS for chronic postsurgical pain (CPSP). The study demonstrated significant pain reduction, improved patient function, and en...

KEY FINDING: The mean VAS score decreased by 6.5 cm after 12 months of treatment, indicating a substantial reduction in pain intensity.

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Pain ManagementTraumaRehabilitation

Pain across traumatic injury groups: A National Institute on Disability, Independent Living, and Rehabilitation Research model systems study

J Trauma Acute Care Surg, 2020 • October 1, 2020

This study investigated pain intensity and interference in individuals with burn, TBI, and SCI compared to the general population, using a custom PROMIS pain interference short form. The results showe...

KEY FINDING: At the start of the study, individuals in all three injury groups (burn, TBI, and SCI) reported significantly higher pain intensity and interference compared to the general population.

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Spinal Cord InjuryPharmacologyPain Management

Neuropathic pain in spinal cord injury: topical analgesics as a possible treatment

Spinal Cord Series and Cases, 2020 • July 29, 2020

This study explores the use of topical analgesics for treating neuropathic pain (NP) in spinal cord injury (SCI) through a literature review and patient interviews. The findings suggest that topical a...

KEY FINDING: The literature review identified seven studies (five case reports and two case series) that evaluated topical analgesics for SCI-related NP, with all reporting a decrease in NP over time.

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Spinal Cord InjuryNeurologyPain Management

Metabolites of neuroinflammation relate to neuropathic pain after spinal cord injury

Neurology, 2020 • August 18, 2020

This study investigated the relationship between neuroinflammatory and neurodegenerative metabolites in the cervical spinal cord and neuropathic pain (NP) in patients with spinal cord injury (SCI). Th...

KEY FINDING: Patients with neuropathic pain (NP) showed increased levels of tCho/mI compared to pain-free patients after spinal cord injury (SCI).

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Spinal Cord InjuryNeurologyPain Management

Peripheral subcutaneous field stimulation for the treatment of spinal cord injury at-level pain: case report, literature review, and 5-year follow-up

Heliyon, 2020 • July 16, 2020

This paper presents a case report of a patient with spinal cord injury (SCI) at-level pain who was successfully treated with peripheral subcutaneous field stimulation (PSFS) and a literature review of...

KEY FINDING: A patient with SCI at-level pain experienced near complete pain relief with PSFS and ceased all narcotic use for pain management.

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PharmacologyPain ManagementRehabilitation

Conditioning open-label placebo: a pilot pharmacobehavioral approach for opioid dose reduction and pain control

PAIN Reports, 2020 • July 20, 2020

This pilot study investigated the feasibility and safety of conditioning open-label placebo (COLP) as a pharmacobehavioral intervention to decrease opioid consumption in patients with pain in comprehe...

KEY FINDING: Conditioning open-label placebo significantly reduced total opioid consumption by the end of the intervention period.

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Spinal Cord InjuryNeurologyPain Management

Spinal cord stimulation attenuates below-level mechanical hypersensitivity in rats after thoracic spinal cord injury

Neuromodulation, 2021 • January 1, 2021

The study evaluated the effects of conventional and high-frequency spinal cord stimulation (SCS) on below-level mechanical hypersensitivity in rats with spinal cord injury (SCI). Both SCS paradigms mo...

KEY FINDING: Both conventional SCS (50 Hz, 80% MoT) and high-frequency SCS (1200 Hz, 40% MoT) attenuated hind paw mechanical hypersensitivity in SCI rats.

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Spinal Cord InjuryNeurologyPain Management

Tissue bridges predict neuropathic pain emergence after spinal cord injury

J Neurol Neurosurg Psychiatry, 2020 • August 11, 2020

This retrospective longitudinal study explored the association between spared spinal cord tissue and neuropathic pain (NP) development after spinal cord injury (SCI). The study found that patients wit...

KEY FINDING: Patients with neuropathic pain had larger ventral tissue bridges at 1 month compared to pain-free patients.

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Spinal Cord InjuryNeurologyPain Management

Effect of non-invasive brain stimulation on neuropathic pain following spinal cord injury A systematic review and meta-analysis

Medicine, 2020 • August 21, 2020

The meta-analysis examined the effect of rTMS and tDCS on neuropathic pain following SCI, using data from multiple studies comparing these treatments to sham stimulations. The study found that rTMS di...

KEY FINDING: rTMS did not show early analgesic effect on NP after SCI compared to sham rTMS.

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