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  4. 10-kHz Spinal Cord Stimulation for Chronic Postsurgical Pain: Results From a 12-Month Prospective, Multicenter Study

10-kHz Spinal Cord Stimulation for Chronic Postsurgical Pain: Results From a 12-Month Prospective, Multicenter Study

Pain Practice, 2020 · DOI: 10.1111/papr.12929 · Published: January 1, 2020

NeurologyPain Management

Simple Explanation

This study investigates the use of 10-kHz spinal cord stimulation (SCS) for treating chronic postsurgical pain (CPSP), a condition often caused by nerve damage during surgery. The study followed patients for 12 months after they received a permanent 10-kHz SCS system to see how effective the treatment was in reducing their pain and improving their quality of life. The results showed significant pain reduction, improved function, and better sleep quality among the patients, suggesting that 10-kHz SCS can be an effective treatment for CPSP.

Study Duration
12 Months
Participants
34 subjects with chronic postsurgical pain
Evidence Level
Prospective, Multicenter Study

Key Findings

  • 1
    The mean VAS score decreased by 6.5 cm after 12 months of treatment, indicating a substantial reduction in pain intensity.
  • 2
    The response rate was 88.0% (22/25) after 12 months, with responders defined as subjects with ≥50% pain relief in VAS score.
  • 3
    62.1% of subjects (18/29) were remitters after 1 year, maintaining VAS scores at ≤3.0 cm, indicating a significant proportion achieved a state of low pain.

Research Summary

This prospective, multicenter study evaluated the effectiveness of 10-kHz SCS for chronic postsurgical pain (CPSP). The study demonstrated significant pain reduction, improved patient function, and enhanced sleep quality over a 12-month period. The findings suggest that 10-kHz SCS is a promising treatment option for CPSP, warranting further investigation.

Practical Implications

Clinical Practice

10-kHz SCS can be considered as a viable treatment option for patients with chronic postsurgical pain who have not responded to conventional medical interventions.

Quality of Life Improvement

The study highlights the potential of 10-kHz SCS to improve patient function, mental health, and sleep quality, thereby enhancing their overall well-being.

Further Research

Further studies are needed to explore the effectiveness of 10-kHz SCS in different subgroups of CPSP patients, including those with nociceptive pain.

Study Limitations

  • 1
    Lack of randomization and a control group
  • 2
    Identical neuro-assessments were not performed across all subjects
  • 3
    Small sample size and varied postsurgical peripheral nerve injury conditions

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