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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Pain Management Research

Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.

Showing 341-350 of 682 results

Pain ManagementGenetics

Perisciatic Nerve Dexmedetomidine Alleviates Spinal Oxidative Stress and Improves Peripheral Mitochondrial Dynamic Equilibrium in a Neuropathic Pain Mouse Model in an AMPK-Dependent Manner

Disease Markers, 2022 • June 20, 2022

The study demonstrates that perineural administration of DEX can alleviate neuropathic pain in mice by activating the AMPK pathway. DEX's beneficial effects involve the restoration of mitochondrial fu...

KEY FINDING: Perineural DEX significantly reversed the decline in mechanical threshold and thermal latency in CCI mice, indicating pain relief.

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Spinal Cord InjuryPain Management

Active or Passive Pain Coping: Which Predicts Daily Physical and Psychosocial Functioning in People With Chronic Pain and Spinal Cord Injury?

Rehabil Psychol, 2022 • August 1, 2022

The study examined the same-day associations of active and passive pain coping with physical and psychosocial outcomes in individuals with SCI and chronic pain. Increased daily passive coping was asso...

KEY FINDING: Increased daily passive coping related to increased same-day depressive symptoms and pain catastrophizing.

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Regenerative MedicinePain ManagementRehabilitation

Mechanisms of Neuropathic Pain and Pain-Relieving Effects of Exercise Therapy in a Rat Neuropathic Pain Model

Journal of Pain Research, 2022 • July 13, 2022

The study investigated the effects of regular exercise on neuropathic pain relief, the underlying mechanisms, and the impact of neuropathic pain on the hippocampus in a rat model. Results showed that ...

KEY FINDING: Regular exercise led to a significant reduction in pain hypersensitivity in rats with CCI at 5 weeks post-injury.

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NeurologyPain ManagementRehabilitation

Bilateral Upper Limb Complex Regional Pain Syndrome (Type 2) in Cervical Spinal Cord Injury: A Case Report

Cureus, 2022 • June 29, 2022

This case report describes a rare instance of bilateral CRPS following a central cord syndrome, highlighting the diagnostic and management complexities. The diagnosis of CRPS was confirmed using a tri...

KEY FINDING: A 68-year-old man developed bilateral upper limb CRPS (Type 2) following a traumatic central cord syndrome after a fall.

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OncologyNeurologyPain Management

Spinal cord stimulation in patients suffering from chronic pain after surgery for spinal intradural tumors: A case report and literature summary

Pain Practice, 2022 • July 1, 2022

This case report presents a successful application of spinal cord stimulation (SCS) in a patient suffering from chronic neuropathic pain after surgical removal of a spinal intradural meningioma. The p...

KEY FINDING: Spinal cord stimulation (SCS) at the Th5 level resulted in significant pain relief for a patient with chronic neuropathic pain following the removal of a Th7 meningioma.

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Spinal Cord InjuryAlternative MedicinePain Management

Effects of Acupuncture on Neuropathic Pain Induced by Spinal Cord Injury: A Systematic Review and Meta-Analysis

Evidence-Based Complementary and Alternative Medicine, 2022 • August 19, 2022

This meta-analysis evaluated the effect of acupuncture on SCI-induced neuropathic pain, including six studies, and indicated that acupuncture has a positive effect. Electroacupuncture (EA) may have be...

KEY FINDING: Acupuncture shows a positive effect on pain severity.

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Spinal Cord InjuryNeurologyPain Management

Spinal cord stimulation for neuropathic pain following traumatic spinal cord injury: a case report

Spinal Cord Series and Cases, 2022 • August 26, 2022

This case report describes the successful use of spinal cord stimulation (SCS) to treat neuropathic pain in a 30-year-old man with an incomplete spinal cord injury (SCI) resulting from gunshot wounds ...

KEY FINDING: A 30-year-old male with a T12 AIS B incomplete spinal cord injury secondary to multiple GSW experienced severe bilateral lower extremity dysesthesias and muscle spasms.

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NeurologyPain Management

Burst and Tonic Spinal Cord Stimulation in the Mechanical Conflict-Avoidance System: Cognitive-Motivational Aspects

Neuromodulation, 2020 • July 1, 2020

This study aimed to assess the cognitive-motivational aspects of Tonic- and Burst SCS-induced pain relief in rats with chronic neuropathic pain using the mechanical conflict-avoidance system (MCAS). Th...

KEY FINDING: MCAS exit latencies differed significantly between Burst SCS and Tonic SCS at 4 mm and 5 mm probe heights, indicating differential effects on cognitive-motivational aspects of pain.

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Spinal Cord InjuryPain ManagementRehabilitation

The Impact of Sub-maximal Exercise on Neuropathic Pain, Inflammation, and Affect Among Adults With Spinal Cord Injury: A Pilot Study

Frontiers in Rehabilitation Sciences, 2021 • October 26, 2021

This study investigated the impact of sub-maximal aerobic exercise on neuropathic pain (NP), inflammation, and psychological affect in adults with spinal cord injury (SCI). The study found that sub-ma...

KEY FINDING: Neuropathic pain decreased immediately post-exercise for both tetraplegics (−60%) and paraplegics (−16%).

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Spinal Cord InjuryMental HealthPain Management

Self-management of pain and depression in adults with spinal cord injury: A scoping review

The Journal of Spinal Cord Medicine, 2020 • May 1, 2020

This scoping review analyzed the extent, range and nature of available research on what is known about the self-management of pain and depression through the use of pharmacological and non-pharmacolog...

KEY FINDING: The majority of studies have focused on self-management of pain, with fewer focusing on depression or both.

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