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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Oncology Research

Browse the latest research summaries in the field of oncology for spinal cord injury patients and caregivers.

Showing 41-50 of 200 results

OncologyDermatology

Marjolin’s ulcer in an ischial pressure sore presented with necrotizing soft tissue infection: A case report

Medicine, 2023 • March 15, 2023

This case report highlights the diagnostic challenges and treatment strategies for Marjolin's ulcer (MU) arising from a pressure sore, initially presenting as necrotizing soft tissue infection (NSTI)....

KEY FINDING: Marjolin's ulcer can mimic necrotizing soft tissue infection, making diagnosis challenging.

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OncologyNeurology

Remote assessment of cognition and quality of life following radiotherapy for glioma: deep-learning-based predictive models and MRI correlates

Journal of Neuro-Oncology, 2023 • April 4, 2023

This study evaluated the relationship between remote cognitive assessments, quality of life, and MRI changes in irradiated glioma patients. Cognitive impairments were correlated with radiotherapy-asso...

KEY FINDING: Cognitive assessments were highly inter-correlated, and impairment was shown between pre- and post-RT findings.

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Cardiovascular ScienceOncologySurgery

Prognostic Factors of the Primary Central Nervous System Lymphoma: Clinical Experience from a Tertiary Care Center in the Middle East

Asian Journal of Neurosurgery, 2023 • March 27, 2023

This retrospective study analyzed 58 patients with PCNSL treated at a tertiary care center in Iran between 2011 and 2018. The study aimed to identify prognostic factors affecting survival and disease...

KEY FINDING: The mean overall survival was 37.4 months, and the mean progression-free survival was 35.1 months.

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Oncology

Separation Operation Followed by Stereotactic Radiotherapy in the Treatment of Spinal Metastasis From Hepatocellular Carcinoma: A Retrospective Cohort Study

Global Spine Journal, 2024 • August 1, 2024

This retrospective cohort study evaluated the clinical efficacy of separation operation combined with postoperative stereotactic radiotherapy (SRT/SRS) in treating hepatocellular carcinoma patients wi...

KEY FINDING: Patients in the SO group demonstrated significantly higher VAS pain scores after treatment compared to the RT group, indicating better pain management with the combined approach.

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Oncology

Assessment of Bone Health Awareness and Education in Breast Cancer Patients with Bone Metastasis in the USA

Journal of Cancer Education, 2023 • April 28, 2023

The study assessed bone health awareness and education in breast cancer patients with bone metastasis in the USA, revealing notable gaps in knowledge regarding bone health, SRE prevention, and screeni...

KEY FINDING: Awareness of general cancer bone health, protection strategies against SREs, and screening tests were low to moderate among the surveyed patients.

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Oncology

Efficacy and safety of CalliSpheres drug-eluting beads for bronchial arterial chemoembolization for refractory non-small-cell lung cancer and its impact on quality of life: A multicenter prospective study

Frontiers in Oncology, 2023 • April 14, 2023

This multicenter prospective study evaluated the efficacy and safety of CalliSpheres drug-eluting beads bronchial arterial chemoembolization (DEB-BACE) for refractory non-small-cell lung cancer (NSCLC...

KEY FINDING: DEB-BACE was effective in treating refractory NSCLC, with an overall response rate (ORR) of 88.37% and a disease control rate (DCR) of 95.35% after 2 months.

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OncologySurgery

Bone-to-Bone Ligament Preserving Laminoplasty with Ultrasonic Osteotome Assistance for Intraspinal Tumors: A Technical Note and Clinical Follow-Up

Orthopaedic Surgery, 2023 • June 1, 2023

The study assesses a novel Bone-to-Bone Ligament Preserving (BLP) laminoplasty technique using an ultrasonic osteotome for the resection of thoracolumbar spinal tumors. Results indicate that BLP lamin...

KEY FINDING: The BLP laminectomy does not increase the risk of dural, spinal cord, or nerve injuries, indicating its safety.

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OncologySurgery

Modified Total en Bloc Spondylectomy with Self-Made Intervertebral Hook Blade in Spinal Tumors: A Retrospective Study

Orthopaedic Surgery, 2023 • June 1, 2023

This study evaluated a modified total en bloc spondylectomy (TES) technique using a homemade intervertebral hook blade for spinal tumors. The modified TES demonstrated a significant reduction in operativ...

KEY FINDING: The modified TES significantly reduced operative time compared to conventional TES.

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Cardiovascular ScienceOncologyRehabilitation

Investigation of the effect of Low‐Level LaserTherapy on arm lymphedema in breast cancer patients: A noninvasive treatment for an intractable morbidity

Health Sci. Rep., 2023 • May 1, 2023

This article aims to study the effect of Low‐Level Laser Therapy (LLLT) on arm lymphedema in patients who have breast cancer. We noted that the average reductions in the circumference and volume of th...

KEY FINDING: The average reductions in the circumference and volume of the affected limb were about 16% and 21.7%, respectively.

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OncologyPharmacologyGenetics

A Serum-Stable Gold(III) Bisphosphine Complex Induces Mild Mitochondrial Uncoupling and In Vivo Antitumor Potency in Triple Negative Breast Cancer

J Med Chem, 2023 • June 22, 2023

This study introduces novel biphenyl Au(III) complexes with bisphosphine ligands, demonstrating their stability and mild mitochondrial uncoupling activity. The complex Au-3 exhibits potent anticancer ...

KEY FINDING: The gold(III) complex Au-3 exhibits significant tumor growth inhibition in a metastatic TNBC mouse model.

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