Browse the latest research summaries in the field of oncology for spinal cord injury patients and caregivers.
Showing 21-30 of 200 results
EMBO Mol Med, 2022 • September 5, 2022
This study introduces a new MALDI-MSI workflow for in situ imaging of glycogen, providing spatial quantification of glycogen levels and architecture in tissues. The method reveals heterogeneous glycog...
KEY FINDING: Glycogen distribution is heterogeneous among different tissues and within different regions of the same tissue in both mice and humans.
Frontiers in Immunology, 2022 • October 5, 2022
This study identifies and characterizes aging/senescence-induced genes (ASIGs) in osteosarcoma to predict clinical prognosis. The researchers used data from public databases to identify three molecula...
KEY FINDING: The study identified three distinct molecular subgroups of osteosarcoma based on the expression of aging/senescence-induced genes (ASIGs), each exhibiting varying levels of immune infiltration.
World Neurosurg, 2023 • January 1, 2023
This study evaluates the outcomes of hybrid therapy (separation surgery followed by SBRT) for colorectal cancer (CRC) patients with metastatic epidural spinal cord compression (MESCC). The results sho...
KEY FINDING: Hybrid-therapy in CRC patients resulted in 86.7% local control at two years after surgery, with limited complications.
Curr. Oncol., 2022 • October 5, 2022
This retrospective study compared urgent surgery followed by radiotherapy (USFR) to urgent radiotherapy alone for treating acute metastatic spinal cord compression (AMSCC). The results indicated that ...
KEY FINDING: Patients treated with urgent surgery followed by radiotherapy (USFR) showed significant improvement in motor strength compared to those treated with radiotherapy alone.
JAAOS Glob Res Rev, 2022 • November 1, 2022
The study introduces a minimally invasive posterior full-endoscopic approach for direct decompression and tumor debulking in the cervical spine for metastatic spinal cord compression resulting from he...
KEY FINDING: Posterior full-endoscopic decompression of cervical metastasis causing unilateral radiculopathy is a feasible surgical technique.
GMJ, 2022 • April 24, 2022
This phase II randomized controlled trial investigated the effects of dimethyl fumarate (DMF) on Karnofsky Performance Status (KPS) and serum S100β levels in newly diagnosed glioblastoma (GBM) patient...
KEY FINDING: DMF administration was associated with a statistically significant increase in KPS scores one month after surgery compared to the control group (P=0.001).
Clinical and Translational Radiation Oncology, 2023 • January 1, 2023
This case report describes a patient with polycythemia vera who developed spinal cord compression due to extramedullary hematopoiesis and was successfully treated with radiotherapy. Radiotherapy, usin...
KEY FINDING: Radiotherapy effectively treated spinal cord compression caused by extramedullary hematopoiesis in a patient with polycythemia vera.
Orthopaedic Surgery, 2023 • January 1, 2023
This study investigates the role of LINC00665 in osteosarcoma (OS) cells, revealing its significant up-regulation and cancer-promoting function. It demonstrates that LINC00665 promotes OS cell prolife...
KEY FINDING: LINC00665 is significantly upregulated in OS cells compared to normal bone cells, suggesting its involvement in OS development.
Annals of Medicine and Surgery, 2022 • September 15, 2022
This case report discusses a rare presentation of primary spinal non-Hodgkin lymphoma in a 32-year-old male who presented with symptoms of impending cauda equina syndrome. The patient was successfully...
KEY FINDING: Primary spinal epidural diffuse large B-cell lymphoma should be considered in patients presenting with back pain and signs of impending cauda equina syndrome.
Neurosurgery, 2023 • March 1, 2023
This retrospective study evaluated the clinical outcomes of hybrid therapy (separation surgery followed by SBRT) in patients with NSCLC and metastatic epidural spinal cord compression (MESCC). The stu...
KEY FINDING: Hybrid therapy (surgery followed by SBRT) resulted in a 95% local control rate at 2 years after surgery in patients with NSCLC and metastatic epidural spinal cord compression (MESCC).