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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Neurorehabilitation Research

Browse the latest research summaries in the field of neurorehabilitation for spinal cord injury patients and caregivers.

Showing 261-270 of 344 results

Regenerative MedicineNeurologyNeurorehabilitation

Cell Therapy From Bench to Bedside Translation in CNS Neurorestoratology Era

Cell Medicine, 2010 • January 1, 2010

Cell-based restorative treatment has become a new trend, and increasing data worldwide have strongly proven that it has a pivotal therapeutic value in CNS disease. Functional neurorestoration has been...

KEY FINDING: The emergence of the term “neurorestoratology,” however, signals the birth of a new discipline, which is equally important in comparison with neurology and neurosurgery

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Spinal Cord InjuryNeurologyNeurorehabilitation

Chondroitinase Combined with Rehabilitation Promotes Recovery of Forelimb Function in Rats with Chronic Spinal Cord Injury

The Journal of Neuroscience, 2011 • June 22, 2011

The study evaluated the effectiveness of ChABC combined with rehabilitation in promoting functional recovery in rats with chronic spinal cord injury (SCI). The results showed that ChABC treatment, whe...

KEY FINDING: ChABC combined with task-specific rehabilitation significantly improved skilled paw reaching in rats with chronic spinal cord injury compared to rehabilitation or ChABC alone.

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Spinal Cord InjuryNeurorehabilitationRehabilitation

Biological Basis of Exercise-based Treatments: Spinal Cord Injury

PM R, 2011 • June 1, 2011

The review emphasizes the importance of task-specific training, intensity, complexity, and timing of exercise interventions for promoting motor relearning and recovery after SCI. It highlights that ex...

KEY FINDING: Spinal learning and synaptic plasticity after SCI depend on intact sensory drive and task-specific training.

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Spinal Cord InjuryAssistive TechnologyNeurorehabilitation

Effects of Assist-As-Needed Upper Extremity Robotic Therapy after Incomplete Spinal Cord Injury: A Parallel-Group Controlled Trial

Front. Neurorobot., 2017 • June 13, 2017

This study evaluated the effectiveness of an assist-as-needed (AAN) robotic therapy for upper extremity rehabilitation in patients with incomplete spinal cord injury (SCI), comparing it to a subject-t...

KEY FINDING: The assist-as-needed (AAN) robotic controller effectively modulated assistance and challenge during therapy sessions, demonstrating its adaptability to individual patient needs.

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Spinal Cord InjuryNeurologyNeurorehabilitation

Learning new movements after paralysis: Results from a home-based study

Scientific Reports, 2017 • June 28, 2017

This study evaluated a body-machine interface (BMI) for assistance and rehabilitation in the home environment, demonstrating consistent motor learning and increased motor performance in cervical SCI p...

KEY FINDING: Participants showed improved cursor control, becoming faster and moving the cursor along straighter lines with practice.

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Spinal Cord InjuryAssistive TechnologyNeurorehabilitation

Robot-applied resistance augments the effects of body weight supported treadmill training on stepping and synaptic plasticity in a rodent model of spinal cord injury

Neurorehabil Neural Repair, 2017 • August 1, 2017

This study investigated the impact of adding robotic-applied resistance to body weight supported treadmill training (BWSTT) on locomotor function and synaptic plasticity in rats with spinal cord injur...

KEY FINDING: Training with horizontal resistance increased step length in spinally contused rats compared to standard BWSTT.

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NeurologyNeurorehabilitation

Treadmill Training with HAL Exoskeleton—A Novel Approach for Symptomatic Therapy in Patients with Limb-Girdle Muscular Dystrophy—Preliminary Study

Frontiers in Neuroscience, 2017 • August 8, 2017

This study investigated the safety and effects of HAL®-supported treadmill therapy on walking function in patients with limb-girdle muscular dystrophy (LGMD). Three LGMD patients underwent an 8-week t...

KEY FINDING: All patients completed the 8-week therapy without any adverse reactions and reported improvements in their endurance.

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Assistive TechnologyNeurologyNeurorehabilitation

Effect of Error Augmentation on Brain Activation and Motor Learning of a Complex Locomotor Task

Frontiers in Neuroscience, 2017 • September 27, 2017

The study evaluated the impact of three error-modulation robotic training strategies on brain activation and motor learning of a complex locomotor task: No perturbation, error amplification, and rando...

KEY FINDING: Training without perturbations enhanced motor learning in initially less skilled subjects, while error amplification benefited better-skilled subjects.

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NeurologyNeuroplasticityNeurorehabilitation

Enhancing Spinal Plasticity Amplifies the Benefits of Rehabilitative Training and Improves Recovery from Stroke

The Journal of Neuroscience, 2017 • November 8, 2017

This study investigates whether intraspinal chondroitinase ABC (ChABC) can augment plasticity of the corticospinal tract (CST) and improve recovery even during chronic stroke. The results showed that ...

KEY FINDING: Chondroitinase ABC (ChABC) injections into the spinal cord during chronic stroke induced significant sprouting of corticospinal axons originating in the peri-infarct cortex, indicating increased structural plasticity.

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Patient ExperienceNeurorehabilitationSocial Support

Peer-led, transformative learning approaches increase classroom engagement in care self-management classes during inpatient rehabilitation of individuals with spinal cord injury

The Journal of Spinal Cord Medicine, 2019 • May 1, 2019

This study evaluated the impact of redesigned self-management education classes on patient engagement during inpatient rehabilitation for individuals with spinal cord injury (SCI). Conventional nurse-...

KEY FINDING: Significantly higher average positive engagement responses were observed in the revised peer-led classes compared to conventional nurse-led classes.

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