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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Neurorehabilitation Research

Browse the latest research summaries in the field of neurorehabilitation for spinal cord injury patients and caregivers.

Showing 1-10 of 344 results

Spinal Cord InjuryNeurorehabilitationBrain Injury

Editorial: Neurorehabilitation in neurotrauma: treating traumatic brain and spinal cord injuries

Front. Hum. Neurosci., 2024 • September 10, 2024

The editorial highlights the global burden of TBI and SCI, emphasizing the need for innovative and effective neurorehabilitation interventions to improve functional recovery and social reintegration f...

KEY FINDING: Mild TBI survivors often experience psychiatric comorbidities like anxiety, depression, and PTSD, along with chronic pain and cardiovascular issues.

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Spinal Cord InjuryNeurologyNeurorehabilitation

Dynamic Motor Compensations with Permanent, Focal Loss of Forelimb Force after Cervical Spinal Cord Injury

JOURNAL OF NEUROTRAUMA, 2013 • February 1, 2013

This study provides a comprehensive quantitative description of motor deficits and compensations from the acute to the late chronic phase after C6 spinal cord hemisection. Permanent impairments were d...

KEY FINDING: A dramatic (50%), immediate and permanent loss of extensor force occurred in the forelimb but not in the hind limb of the injured side.

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Regenerative MedicineNeurologyNeurorehabilitation

Skin-Derived Precursor Cells Promote Angiogenesis and Stimulate Proliferation of Endogenous Neural Stem Cells after Cerebral Infarction

BioMed Research International, 2015 • January 5, 2015

The study investigated the therapeutic potential of skin-derived precursor cells (SKPs) in a rat model of cerebral ischemia, finding that SKPs transplantation improved behavioral measures of neurologi...

KEY FINDING: SKPs transplantation could improve the behavioral measures of neurological deficit.

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Spinal Cord InjuryGeneticsNeurorehabilitation

The NFATC2/Nrf2 cascade regulates spinal cord ischemia-reperfusion injury by controlling inflammation, apoptosis and oxidative stress

Regenerative Therapy, 2025 • November 20, 2024

Spinal cord ischemia/reperfusion (IR) injury (SCII) can cause major autonomic, sensory, and motor damage and loss. The upregulation of Nrf2, a primary orchestrator of the oxidative stress response, ha...

KEY FINDING: Nrf2 and NFATC2 levels were reduced in PC12 cells after OGD/R treatment.

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Spinal Cord InjuryNeurorehabilitationRehabilitation

On the role of visual feedback and physiotherapist‑patient interaction in robot‑assisted gait training: an eye‑tracking and HD‑EEG study

Journal of NeuroEngineering and Rehabilitation, 2024 • December 3, 2024

This study investigated the impact of visual feedback type and physiotherapist-patient interaction level on patient engagement during robot-assisted gait training (t-RAGT) using eye-tracking (ET) and ...

KEY FINDING: The type of visual feedback significantly affects all eye-tracking metrics across monitor, physiotherapist, and surrounding areas of interest.

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Spinal Cord InjuryNeurologyNeurorehabilitation

Effective Connectivity in Spinal Cord Injury-Induced Neuropathic Pain

Sensors, 2022 • August 23, 2022

The study aimed to differentiate the effects of spinal cord injury (SCI) and central neuropathic pain (CNP) on effective connectivity during motor imagery of legs. Multichannel EEG was recorded during...

KEY FINDING: Subacute SCI appears to decrease connectivity from the supplementary motor area and increase connectivity to and from the secondary somatosensory cortex.

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NeurologyNeurorehabilitation

Short-term spinal cord stimulation in treating disorders of consciousness monitored by resting-state fMRI and qEEG: The first case report

Frontiers in Neurology, 2022 • October 25, 2022

This case report presents the first published case of short-term spinal cord stimulation (st-SCS) in a patient with disorders of consciousness (DOC). The patient, a 35-year-old male with severe trauma...

KEY FINDING: The patient improved from a vegetative state/unwakefulness syndrome to an emergence from a minimally conscious state after st-SCS treatment.

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Spinal Cord InjuryNeurologyNeurorehabilitation

Training with noninvasive brain–machine interface, tactile feedback, and locomotion to enhance neurological recovery in individuals with complete paraplegia: a randomized pilot study

Scientific Reports, 2022 • December 6, 2022

This study investigated the effect of assisted locomotion training plus noninvasive BMI and tactile feedback to induce partial neurological recovery for people with the most severe loss of sensory and...

KEY FINDING: Locomotion training alone can induce some level of neurological recovery in sensorimotor-complete SCI.

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Spinal Cord InjuryPharmacologyNeurorehabilitation

Bumetanide increases postsynaptic inhibition after chronic SCI and decreases presynaptic inhibition with step-training

J Physiol, 2023 • April 1, 2023

This study provides the first evidence that bumetanide increases postsynaptic inhibition of the H-reflex after chronic SCI. By using in vivo intracellular recordings of motoneurons, we show that bumet...

KEY FINDING: A prolonged bumetanide treatment increases postsynaptic inhibition towards values observed in step-trained animals.

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Alternative MedicineNeurorehabilitationBiomechanics

Does Music Therapy Improve Gait after Traumatic Brain Injury and Spinal Cord Injury? A Mini Systematic Review and Meta-Analysis

Brain Sci., 2023 • March 21, 2023

This mini-review and meta-analysis investigated the impact of music therapy (MT) on improving gait in individuals with traumatic brain injury (TBI) and spinal cord injury (SCI). The meta-analysis reve...

KEY FINDING: MT shows positive effects on spatiotemporal aspects of gait in TBI, with medium effect improvements (Hedge’s g: 0.52).

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