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  4. Effects of Assist-As-Needed Upper Extremity Robotic Therapy after Incomplete Spinal Cord Injury: A Parallel-Group Controlled Trial

Effects of Assist-As-Needed Upper Extremity Robotic Therapy after Incomplete Spinal Cord Injury: A Parallel-Group Controlled Trial

Front. Neurorobot., 2017 · DOI: 10.3389/fnbot.2017.00026 · Published: June 13, 2017

Spinal Cord InjuryAssistive TechnologyNeurorehabilitation

Simple Explanation

This study investigates whether a robot-assisted therapy, which adapts to a patient's needs during movement, can improve arm function in individuals with incomplete spinal cord injuries. The robot adjusts the amount of help it gives based on the patient's performance. Seventeen patients with incomplete spinal cord injuries participated in the study. They were divided into two groups: one received the adaptive robot therapy (AAN), and the other received a standard, non-adaptive robot therapy (ST). While the study didn't find significant improvements in standard clinical measures of arm function, it did find that the adaptive robot therapy group showed greater improvements in the quality of their movements as measured by the robot itself.

Study Duration
3-4 weeks of robotic training, with follow-ups at 1 week, 2 weeks, and 2 months
Participants
17 patients with incomplete spinal cord injury (AIS C and D levels)
Evidence Level
Level 2: Parallel-Group Controlled Trial, development-of-concept pilot study

Key Findings

  • 1
    The assist-as-needed (AAN) robotic controller effectively modulated assistance and challenge during therapy sessions, demonstrating its adaptability to individual patient needs.
  • 2
    No statistically significant change was measured in either group of subjects for the primary outcome measure, the pre–post difference in ARAT score.
  • 3
    Ancillary analysis of secondary outcome measures obtained via robotic testing indicates gradual improvement in movement quality during the therapy program in both groups, with the AAN controller affording greater increases in movement quality over the ST controller.

Research Summary

This study evaluated the effectiveness of an assist-as-needed (AAN) robotic therapy for upper extremity rehabilitation in patients with incomplete spinal cord injury (SCI), comparing it to a subject-triggered (ST) control method. The AAN controller was validated in its ability to modulate assistance and challenge during therapy. However, the study did not demonstrate statistically significant gains in arm function based on the primary clinical outcome measure (ARAT score). Despite the lack of significant clinical improvement, robotic testing showed gradual improvement in movement quality in both groups, with the AAN controller showing greater increases in movement quality compared to the ST controller, suggesting potential benefits of subject-adaptive robotic therapy.

Practical Implications

Personalized Therapy

Adaptive robotic therapy can be tailored to individual patient needs, potentially maximizing motor recovery.

Objective Assessment

Robotic measures can provide objective and detailed assessments of movement quality, complementing traditional clinical assessments.

Further Research

Larger and longer-term studies are needed to confirm the clinical benefits of AAN robotic therapy for incomplete SCI.

Study Limitations

  • 1
    Small sample size
  • 2
    Lack of statistically significant gains in clinical outcome measures
  • 3
    High variability of subject populations

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