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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Neurorehabilitation Research

Browse the latest research summaries in the field of neurorehabilitation for spinal cord injury patients and caregivers.

Showing 11-20 of 344 results

Regenerative MedicineNeurorehabilitationBiomedical

Recent advances in the combination of cellular therapy with stem cells and nanoparticles after a spinal cord injury

Frontiers in Neurology, 2023 • April 26, 2023

This review explores the potential of combining cellular therapy with stem cells and nanoparticles to treat spinal cord injuries (SCI). It highlights the limitations of single treatments and the promi...

KEY FINDING: The combination of nanoparticles and stem cells in animal models of SCI has a positive impact on neuroprotection and neuroregeneration.

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NeurologyNeurorehabilitation

Neutralizing RGMa with Elezanumab Promotes Cerebroprotection and Recovery in Rabbit Middle Cerebral Artery Occlusion

Translational Stroke Research, 2024 • June 16, 2023

These studies demonstrate that elezanumab administered 6 h after pMCAO enhanced recovery of neuromotor function and suppressed neuroinflammation and astrogliosis, which was also observed when elezanum...

KEY FINDING: Elezanumab, administered 6 h after pMCAO, significantly reduced peak neuromotor deficits 48 h post stroke.

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NeurologyNeurorehabilitation

What Else Can Be Done by the Spinal Cord? A Review on the Effectiveness of Transpinal Direct Current Stimulation (tsDCS) in Stroke Recovery

Int. J. Mol. Sci., 2023 • June 15, 2023

This review explores the effectiveness of transpinal direct current stimulation (tsDCS) for motor and cognitive recovery, particularly in stroke patients, by analyzing existing literature on its effec...

KEY FINDING: tsDCS can induce local and cortical neuroplastic changes, influencing activity in cortical and corticospinal pathways in humans.

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Spinal Cord InjuryPain ManagementNeurorehabilitation

A Nutritional Supplement as Adjuvant of Gabapentinoids for Adults with Neuropathic Pain following Spinal Cord Injury and Stroke: Preliminary Results

Healthcare, 2023 • September 16, 2023

This study evaluated the effects of NACVAN®, a commercially available nutraceutical, as an add-on to gabapentinoids for treating pain in patients with central neuropathic pain (CNP) resulting from spi...

KEY FINDING: There was a significant reduction in pain intensity from baseline to 3 weeks (p = 0.021) and from baseline to 6 weeks (p = 0.011).

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NeurologyOrthopedicsNeurorehabilitation

Upper extremity asymmetry due to nerve injuries or central neurologic conditions: a scoping review

Journal of NeuroEngineering and Rehabilitation, 2023 • November 1, 2023

This review documents various tests/techniques/sensors used to assess UE asymmetry in individuals with neurological conditions/injuries between 2000-2022. The review identifies trends in studies, clas...

KEY FINDING: Stroke was the most studied condition, followed by cerebral palsy, with kinematics and strength measurement tests being the most frequently used tests.

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Alternative MedicineNeurorehabilitation

Can alternative medical methods evoke somatosensory responses and functional improvement?

Heliyon, 2024 • April 23, 2024

The study explores the potential of alternative medicine, specifically cauterization, to improve functional recovery after central nervous system injuries. It compares cauterization to other methods l...

KEY FINDING: Patients treated with cautery showed improvements in motor skills, including walking and limb movement.

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NeurologyNeurorehabilitation

Bimanual coordination and spinal cord neuromodulation: how neural substrates of bimanual movements are altered by transcutaneous spinal cord stimulation

Journal of NeuroEngineering and Rehabilitation, 2024 • June 6, 2024

This study examined the impact of cervical tSCS on cortical activity and motor performance during unimanual and bimanual arm movements in neurologically intact individuals. The results showed that tSC...

KEY FINDING: tSCS improved movement time and error during a bimanual common-goal movement.

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Spinal Cord InjuryAssistive TechnologyNeurorehabilitation

Quantifying Treatments as Usual and with Technologies in Neurorehabilitation of Individuals with Spinal Cord Injury

Healthcare, 2024 • September 13, 2024

This study quantifies the distribution of conventional (TAU) and technology-aided (TWT) treatments in SCI neurorehabilitation, assessing technology adoption and resource usage based on therapeutic goa...

KEY FINDING: Technology adoption averaged around 30% across all participants.

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HealthcareNeurorehabilitation

Criteria and Indicators for Centers of Clinical Excellence in Stroke Recovery and Rehabilitation: A Global Consensus Facilitated by ISRRA

Neurorehabilitation and Neural Repair, 2024 • February 1, 2024

This study defines key criteria and measurable indicators for Centers of Clinical Excellence (CoCE) in stroke recovery and rehabilitation. The criteria and indicators are designed to be globally appli...

KEY FINDING: Seven key criteria for CoCE were identified and ranked, including optimal outcomes, research culture, and inter-professional working.

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Spinal Cord InjuryAssistive TechnologyNeurorehabilitation

Retraining walking over ground in a powered exoskeleton after spinal cord injury: a prospective cohort study to examine functional gains and neuroplasticity

Journal of NeuroEngineering and Rehabilitation, 2019 • August 30, 2019

This study evaluated the effectiveness of the ReWalk exoskeleton for individuals with spinal cord injury, focusing on training progression, neuroplasticity, and usability in home environments. The res...

KEY FINDING: Walking proficiency in the ReWalk requires about 45 sessions of training.

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