A Nutritional Supplement as Adjuvant of Gabapentinoids for Adults with Neuropathic Pain following Spinal Cord Injury and Stroke: Preliminary Results

This study investigates whether a nutritional supplement called NACVAN®, when combined with gabapentinoids, can help reduce pain in patients with central neuropathic pain (CNP) caused by spinal cord injury or stroke. The researchers measured pain intensity, neuropathic symptoms, and quality-of-life at the beginning of the study, after 3 weeks, and after 6 weeks of treatment with NACVAN®. Preliminary results showed that NACVAN® may have a beneficial effect when used with gabapentinoids to alleviate pain in patients with CNP due to SCI or stroke, without causing adverse effects.

• 1
  There was a significant reduction in pain intensity from baseline to 3 weeks (p = 0.021) and from baseline to 6 weeks (p = 0.011).
• 2
  The study found a significant reduction in neuropathic symptoms from baseline to 3 weeks (p = 0.024) and from baseline to 6 weeks (p = 0.003).
• 3
  Evoked pain was significantly reduced from baseline to 6 weeks (p = 0.048).