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  4. What Else Can Be Done by the Spinal Cord? A Review on the Effectiveness of Transpinal Direct Current Stimulation (tsDCS) in Stroke Recovery

What Else Can Be Done by the Spinal Cord? A Review on the Effectiveness of Transpinal Direct Current Stimulation (tsDCS) in Stroke Recovery

Int. J. Mol. Sci., 2023 · DOI: 10.3390/ijms241210173 · Published: June 15, 2023

NeurologyNeurorehabilitation

Simple Explanation

The spinal cord, traditionally viewed as a simple connection between the brain and body, is now recognized for its role in motor skills and cognitive functions. Transpinal direct current stimulation (tsDCS) is a non-invasive technique that delivers a weak electrical current to the spinal cord, promoting neuroplasticity and potentially aiding motor and cognitive recovery after stroke. This review analyzes studies on tsDCS's impact on motor improvement in animals and healthy individuals, as well as its effectiveness in motor and cognitive recovery in stroke patients, suggesting tsDCS may be a valuable addition to post-stroke rehabilitation.

Study Duration
Not specified
Participants
Animals, healthy subjects, and post-stroke populations
Evidence Level
Review

Key Findings

  • 1
    tsDCS can induce local and cortical neuroplastic changes, influencing activity in cortical and corticospinal pathways in humans.
  • 2
    Studies on animals suggest that both anodal and cathodal tsDCS induce local and cortical plastic changes in rat motoneurons.
  • 3
    Anodal tsDCS enhances locomotor skills and reduces fatigue in humans, while cathodal tsDCS can transiently facilitate peak acceleration in motor tasks.

Research Summary

This review explores the effectiveness of transpinal direct current stimulation (tsDCS) for motor and cognitive recovery, particularly in stroke patients, by analyzing existing literature on its effects on animals, healthy subjects, and post-stroke populations. The analysis reveals that tsDCS can induce neuroplastic changes at both spinal and cortical levels, influencing motor neuron activity and improving locomotor skills, sleep, and potentially reducing spasticity in stroke patients when combined with other therapies. The review concludes that tsDCS shows promise as a therapeutic adjunctive approach in neurorehabilitation, especially for motor and cognitive disorders post-stroke, while acknowledging the need for standardized protocols to optimize its effectiveness.

Practical Implications

Potential Therapeutic Adjunct

tsDCS may serve as a valuable addition to traditional neurorehabilitation strategies for stroke patients, enhancing motor and cognitive recovery.

Enhanced Athletic Performance

The combination of tsDCS with transcranial direct current stimulation (tDCS) could improve athletic performance by enhancing selective attention and reaction times.

Targeted Cognitive Therapy

tsDCS may offer a targeted approach for improving language recovery, particularly in action verb naming, by influencing sensorimotor networks in the brain.

Study Limitations

  • 1
    Heterogeneity of protocols and electrode montages
  • 2
    Lack of standardized tsDCS parameters for optimal outcomes
  • 3
    Need for studies determining long-term tsDCS effects

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