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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Neurorehabilitation Research

Browse the latest research summaries in the field of neurorehabilitation for spinal cord injury patients and caregivers.

Showing 141-150 of 344 results

Assistive TechnologyNeurorehabilitationBiomechanics

Persistent Effect of Gait Exercise Assist Robot Training on Gait Ability and Lower Limb Function of Patients With Subacute Stroke: A Matched Case–Control Study With Three-Dimensional Gait Analysis

Frontiers in Neurorobotics, 2020 • July 24, 2020

This study investigated the persistent effects of gait exercise assist robot (GEAR) training on gait ability and lower limb function in subacute stroke patients using a matched case-control design wit...

KEY FINDING: Patients in the GEAR group showed significant improvement in FIM-walk score and SIAS-L/E score at discharge compared to post-training, indicating improved motor skills and functional gait.

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NeurorehabilitationBiomechanics

Short-Step Adjustment and Proximal Compensatory Strategies Adopted by Stroke Survivors With Knee Extensor Spasticity for Obstacle Crossing

Frontiers in Bioengineering and Biotechnology, 2020 • August 6, 2020

This study examined the step adjustment and compensatory strategies used by stroke survivors with knee extensor spasticity during obstacle crossing. The results revealed that stroke survivors with kne...

KEY FINDING: Stroke survivors with knee extensor spasticity use a short-step strategy before the obstacle to enhance accuracy and maintain stability.

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Spinal Cord InjuryAssistive TechnologyNeurorehabilitation

Is Virtual Reality Effective for Balance Recovery in Patients with Spinal Cord Injury? A Systematic Review and Meta-Analysis

Journal of Clinical Medicine, 2020 • September 4, 2020

This systematic review and meta-analysis aimed to analyze the effectiveness of VR interventions on balance recovery in patients with SCI, compared to CPT. The results of this systematic review and meta...

KEY FINDING: Statistical analysis showed favorable results for balance measured by the modified Functional Reach Test (standardized mean difference (SMD) = 3.42; 95% confidence interval: 2.54 to 4.29) and by the t-shirt test (SMD= −2.29; 95% confidence interval: −3.00 to −1.59).

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Spinal Cord InjuryPain ManagementNeurorehabilitation

Conditioned Pain Modulation Decreases Over Time in Patients With Neuropathic Pain Following a Spinal Cord Injury

Neurorehabilitation and Neural Repair, 2020 • November 1, 2020

This longitudinal study investigated the evolution of conditioned pain modulation (CPM) over time in patients with spinal cord injury (SCI) and explored its relationship with clinical pain. The study ...

KEY FINDING: A significant decrease in the efficacy of conditioned pain modulation (CPM) was observed over time in patients with SCI.

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Spinal Cord InjuryNeurologyNeurorehabilitation

The neuroanatomical–functional paradox in spinal cord injury

Nature Reviews Neurology, 2021 • January 1, 2021

The neuroanatomical–functional paradox describes the discrepancy between lesion size and functional outcome after spinal cord injury (SCI). This paradox is influenced by various factors, including les...

KEY FINDING: The magnitude of functional recovery can vary considerably between individuals, even if the location and size of the primary lesion seems to be similar.

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Assistive TechnologyNeurorehabilitation

Active proportional electromyogram controlled functional electrical stimulation system

Scientific Reports, 2020 • December 4, 2020

The study introduces a novel Active FES system that utilizes an adaptive filtering technique to extract voluntary EMG from muscles during FES, addressing the challenge of electrical artefact contamina...

KEY FINDING: The Active FES system effectively extracts voluntary EMG from muscles under FES using an adaptive filtering technique, outperforming the classic comb filtering method.

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Spinal Cord InjuryNeurologyNeurorehabilitation

Epidural Electrical Stimulation of the Lumbosacral Spinal Cord Improves Trunk Stability During Seated Reaching in Two Humans With Severe Thoracic Spinal Cord Injury

Front. Syst. Neurosci., 2020 • November 19, 2020

This study evaluated the effects of epidural spinal electrical stimulation (ES) on seated reaching performance in two individuals with chronic, complete thoracic spinal cord injury (SCI). The results ...

KEY FINDING: Epidural stimulation (ES) enhanced seated reaching-performance of individuals with chronic SCI.

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Spinal Cord InjuryNeurorehabilitation

Use of Surface EMG in Clinical Rehabilitation of Individuals With SCI: Barriers and Future Considerations

Frontiers in Neurology, 2020 • December 18, 2020

This perspective discusses barriers restricting the widespread use of sEMG in clinical rehabilitation of individuals with spinal cord injury (SCI). The barriers include time-consuming aspects of sEMG,...

KEY FINDING: Limited clinician time is a significant barrier to the uptake of sEMG technology in clinics due to time-consuming setup and data collection processes.

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Spinal Cord InjuryPharmacologyNeurorehabilitation

Enhancing KCC2 activity decreases hyperreflexia and spasticity after chronic spinal cord injury

Exp Neurol, 2021 • April 1, 2021

This study investigates the effects of pharmacologically increasing KCC2 activity using CLP257 on spasticity symptoms after chronic SCI in rats. The study also explores how this pharmacological approa...

KEY FINDING: Increasing KCC2 activity with CLP257 improved the rate-dependent depression of the H-reflex in sedentary animals after chronic SCI, indicating improved reflex modulation.

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Assistive TechnologyNeurologyNeurorehabilitation

Virtual Reality Applications for Neurological Disease: A Review

Frontiers in Robotics and AI, 2019 • October 16, 2019

This systematic review examines emerging VR applications developed over the last 5 years for neurological diseases, focusing on fully-immersive VR systems. The review covers conditions like dementia, ...

KEY FINDING: VR shows promising potential for neurorehabilitation, with most studies illustrating positive outcomes in treating nervous system injury linked to functional disability.

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