Neurorehabilitation Research

KEY FINDING: The proposed neuroprosthesis was able to generate individually fitted stimulation patterns for three of the participants with incomplete SCI.

KEY FINDING: Systems capable of self-adjustment and closed-loop control are crucial for modulating assistance in individual conditions to adequately assist the patient.

KEY FINDING: Spinal cord injury enables plasticity by down-regulating the Cl− co-transporter KCC2, which reduces GABAergic inhibition, enabling learning but also fueling over-excitation and nociceptive sensitization.

KEY FINDING: Actovegin® improves tissue oxygen and glucose consumption and energy production, especially in the hippocampus, an area linked to learning and memory.

KEY FINDING: Combined AIH and TST produce a synergistic effect on motor plasticity, resulting in greater functional benefits than either treatment alone.

KEY FINDING: Peripheral nerve interfaces and brain-machine interfaces share characteristics that allow for concurrent development.

KEY FINDING: Multidisciplinary stroke unit care reduces the rate of death or institutionalized care and death or dependence after stroke, without significantly increasing length of stay, and independent of age, sex, or stroke severity.

KEY FINDING: EWT with SCES significantly increased foot loading forces and could decrease their asymmetry.

KEY FINDING: FES therapy can produce significant changes in arm and hand function, as shown in pilot studies and randomized control trials.

KEY FINDING: Improvements were seen for four of the five participants on at least one of the clinical scales following completion of the training intervention.