Activities of daily living and lesion position among multiple sclerosis patients by Bayes network

Multiple sclerosis (MS) is an autoimmune disease affecting the central nervous system, often leading to cognitive and physical impairments. This study investigates the relationship between the location of brain lesions and the ability of MS patients to perform daily activities. Using data from 238 MS patients in Shanghai, China, the researchers analyzed MRI scans to identify lesions in different areas of the brain and spinal cord. They then used a Bayes network to determine how these lesions correlate with the patients' ability to perform daily activities such as bathing, dressing, and walking. The study found that lesions in the cerebrum, spinal cord, and supratentorial region (the upper part of the brain) had a significant impact on daily living activities. Conversely, lesions in the brainstem were found to have little influence on these activities.

• 1
  Lesions in the cerebrum, spinal cord, and supratentorial position are likely to influence activities of daily living in multiple sclerosis patients.
• 2
  Brainstem lesions were found to have very little influence on the activities of daily living.
• 3
  When the cerebrum was lesioned and the activities of daily living were basically normal, with only help in bathing needed, the probability of supratentorial lesion peaked (96.4%), suggesting the cerebral lesion mainly occurs in the supratentorial site.