Browse the latest research summaries in the field of immunology for spinal cord injury patients and caregivers.
Showing 291-300 of 730 results
Neural Regen Res, 2021 • September 1, 2021
The study investigated the role of HMGB1 in the inflammatory response of astrocytes following spinal cord injury (SCI) in rats using transcriptome sequencing and in vitro experiments. The results show...
KEY FINDING: HMGB1/TLR4 axis is involved in astrocyte inflammatory response through regulation of COX2/PGE2 signaling.
PM R, 2021 • December 1, 2021
This mixed-methods study explores the experiences of veterans with SCI regarding annual urine screening and antibiotic use for UTIs. It aims to understand patient adherence, knowledge, and attitudes t...
KEY FINDING: Veterans with SCI generally report high adherence to prescribed antimicrobial courses and high levels of satisfaction with current outpatient VHA SCI bladder care.
Spinal Cord Series and Cases, 2021 • June 1, 2021
This study examined the impact of a high-fat/high-carbohydrate (HFHC) meal on circulating immune cell numbers in individuals with chronic spinal cord injury (SCI). Contrary to the hypothesis, immune c...
KEY FINDING: A significant time × condition interaction effect was observed in CD3+, CD4+, and CD8+ T cells, as well as CD56+ and CD3+/CD56+ natural killer (NK) cells.
Annals of Rehabilitation Medicine, 2021 • June 14, 2021
This study evaluated the risk of post-urodynamic study (UDS) urinary tract infection (UTI) in spinal cord injury (SCI) patients with pre-UDS pyuria. The study found no statistically significant differ...
KEY FINDING: The study found no statistically significant difference in the prevalence of post-UDS UTI between patients with and without pyuria before the UDS.
World Journal of Clinical Cases, 2021 • June 6, 2021
This case report discusses a 45-year-old woman with NMOSD, Sjogren's syndrome, spinal cord injury, and deep venous thrombosis who underwent rehabilitation and pharmacotherapy. The patient's condition ...
KEY FINDING: The patient with NMOSD, spinal cord injury, Sjogren's syndrome, and deep venous thrombosis showed considerable improvement after rehabilitation and pharmacotherapy.
Muscle & Nerve, 2021 • July 9, 2021
This letter describes the COVID-19 prevalence and case fatality rate (CFR), as reported by aggregate summaries from VINCI, as well as the characteristics and outcomes, as reported by the VHA-SCI/D Reg...
KEY FINDING: Veterans with ALS were 3.0 times more likely to die within 30 days of a COVID-19 diagnosis compared to the overall veteran population (CI: 1.9–4.9, p < .001).
Spinal Cord, 2021 • August 17, 2021
This review indicates a similar rate of COVID-19 Vaccine breakthrough in individuals with SCI/D compared to residents of SNFs in which frequent surveillance testing is occurring. The predominance of a...
KEY FINDING: COVID-19 vaccine breakthrough was identified in 17 out of 8319 (0.20%) of fully vaccinated Veterans with SCI/D as of April 20, 2021.
Frontiers in Immunology, 2021 • August 11, 2021
This study demonstrates that infiltrated neutrophils produce NETs at the injury site, exacerbating secondary injury in SCI by promoting neuroinflammation and disrupting the blood-spinal cord barrier. ...
KEY FINDING: Infiltrated neutrophils produce NETs at the epicenter of the SCI, which contributes to secondary injury.
BMC Infect Dis, 2021 • September 15, 2021
The study evaluated SARS-CoV-2 antibody prevalence and asymptomatic infection rates among Austrian hospital staff. Key findings include a low seroprevalence (0.82%), a significant proportion of asympt...
KEY FINDING: Only 0.82% of participants had positive antibodies confirmed via neutralization test during the study.
Surgical Neurology International, 2021 • August 30, 2021
This case report describes the successful use of aneurysm clips to repair a cisterna chyli (CC) injury sustained during a thoracolumbar fusion. This technique has not been previously described in lite...
KEY FINDING: Aneurysm clips can be safely and effectively used to repair cisterna chyli injuries during spinal surgery.