Immunology Research

KEY FINDING: ACOD1 attenuated neuroinflammation and oxidative stress after spinal cord injury.

KEY FINDING: Genetic deletion of CD11b increases the neuroinflammation in the injured spinal cord tissue.

KEY FINDING: The patient developed GFAP-A shortly after receiving the SARS-CoV-2 vaccine, suggesting a possible link between vaccination and the onset of the autoimmune condition.

KEY FINDING: MSC and HSC therapies can improve disease activity and severity in organs affected by SLE, such as the kidney, lung, liver, and bone.

KEY FINDING: ADAM8 up-regulation in microglia is associated with inflammation after SCI.

KEY FINDING: Ginger treatment significantly improved locomotor activity and reduced thermal hyperalgesia in CCI rats, indicating a positive impact on pain-related behaviors.

KEY FINDING: Pregabalin treatment significantly reduced neuronal damage in both the brain and spinal cord of neuropathic pain rats compared to the control group.

KEY FINDING: The patient developed a spinal epidural abscess and bacteremia secondary to the hematogenous spread of Bacteroides spp. from a hospital-acquired stage 4 sacral pressure ulcer.

KEY FINDING: This study examines the upstream and downstream pathways involved in inflammation caused by TBI and SCI, including interleukins, T cells, NK cells, XCL1, XCR1+ dendritic cells, and interferon-gamma, describing their proinflammatory effect.

KEY FINDING: Multi-drug and short-term immunosuppression regimens are commonly employed in stem cell trials involving retinal and neural cells.