Browse the latest research summaries in the field of gastroenterology for spinal cord injury patients and caregivers.
Showing 101-110 of 136 results
Evidence-Based Complementary and Alternative Medicine, 2016 • August 22, 2016
This study aimed to evaluate the effects and safety of Poncirus fructus (PF) in spinal cord injury (SCI) patients with neurogenic bowel. The results indicated that PF administration significantly impr...
KEY FINDING: The morphological feature of the stool showed a statistically significant difference after PF administration.
BioMed Research International, 2016 • November 1, 2016
This study investigated the effects of electroacupuncture (EA) on intestinal movement and the expression of the Per2 gene in rats with spinal cord injury (SCI). The research aimed to determine if EA c...
KEY FINDING: EA shortened the stool efflux time and increased the dry fecal weight within 24 h in SCI rats, indicating improved intestinal transmission function.
Annals of Rehabilitation Medicine, 2011 • October 1, 2011
This study investigated the impact of spinal cord injury (SCI) on colonic contractility and muscarinic receptor subtypes in rats. The researchers aimed to determine how SCI-induced changes in M2 and M...
KEY FINDING: SCI rats showed an increased response to Ach in the proximal colon compared to control rats, indicating altered contractility after SCI.
Top Spinal Cord Inj Rehabil, 2016 • April 1, 2016
This study investigated the behaviors used by individuals with chronic SCI to manage neurogenic bowel and bladder, exploring the relationship between these behaviors and outcomes related to health and...
KEY FINDING: Methods used to manage neurogenic bowel and bladder are multifaceted, with consistency in some areas but significant variations based on neurological status and quality of life.
The Journal of Spinal Cord Medicine, 2018 • March 1, 2018
This study demonstrates that a multi–day, inpatient bowel preparation regimen is a tolerable, safe method of achieving a high percentage of adequate-quality bowel preparations in a population of patie...
KEY FINDING: The full bowel preparation was tolerated by 91% of inpatients, indicating good tolerability of the regimen.
World J Gastroenterol, 2010 • November 21, 2010
This study investigated colonic motility, specifically high amplitude propagating contractions (HAPC), in individuals with spinal cord injury (SCI) compared to healthy controls. The key finding was th...
KEY FINDING: High amplitude propagating contractions (HAPC) were absent in individuals with spinal cord injury (SCI) during pre-sleep, sleep, and post-sleep phases.
BioMed Research International, 2017 • August 30, 2017
This study investigated the relationship between liver adiposity, measured by MRI, and metabolic profile in men with chronic spinal cord injury (SCI). The results showed that increased liver fat was a...
KEY FINDING: Fat signal fraction (FSF) in the liver was positively related to triglycerides (TG), non-HDL-C, fasting glucose, and HbA1c, indicating a link between liver fat and poorer lipid and glucose control.
Spinal Cord, 2018 • March 1, 2018
The study compared transdermal administration of neostigmine/glycopyrrolate via iontophoresis to intravenous administration for bowel evacuation in spinal cord injury patients. Transdermal delivery re...
KEY FINDING: Transdermal administration of neostigmine/glycopyrrolate by iontophoresis appears to be a practical, safe, and effective approach to induce bowel evacuation in individuals with spinal cord injury.
BioMed Research International, 2017 • November 16, 2017
This study investigates the therapeutic effects of abdominal manual therapy (AMT) on bowel dysfunction after spinal cord injury (SCI), focusing on interstitial cells of Cajal (ICCs) and c-kit expressi...
KEY FINDING: AMT significantly increased weight, shortened time to defecation, increased feces amounts, and improved fecal pellet traits and colon histology in SCI rats.
Spinal Cord Series and Cases, 2018 • January 1, 2018
Neurogenic bowel dysfunction (NBD) significantly impacts quality of life after spinal cord injury (SCI). International standards were developed to standardize communication about autonomic function af...
KEY FINDING: Determination of neurologic level of injury alone is insufficient for assessing autonomic function; surrogate markers are necessary.