Browse the latest research summaries in the field of endocrinology for spinal cord injury patients and caregivers.
Showing 161-170 of 217 results
Arch Phys Med Rehabil, 2019 • June 1, 2019
This study investigated glucose metabolism differences among women with paraplegic and tetraplegic spinal cord injury (SCI) compared to able-bodied (AB) women, adjusting for body composition differenc...
KEY FINDING: Women with tetraplegia had higher glucose, insulin, and C-peptide concentrations at minute 120 during the oral glucose tolerance test (OGTT) compared to women with paraplegia and able-bodied women, even after adjusting for total body lean mass and percentage fat mass.
Spinal Cord, 2019 • March 1, 2019
The findings demonstrated that multiple indicators of cardiometabolic health and body composition variables are associated with serum T levels in men with motor complete SCI. The low range serum T gro...
KEY FINDING: Low range serum T group had greater total (9.6%, P= 0.04) percentage fat mass and visceral adipose tissue (VAT) area (72%, P= 0.01) compared to normal range serum T group.
Journal of Clinical Medicine, 2019 • January 23, 2019
This study investigated the effects of environmental lighting conditions on neural repair following experimental spinal cord injury (SCI) in rats, focusing on the role of endogenous melatonin. The key...
KEY FINDING: Constant darkness after SCI in rats led to a significant increase in motor recovery and body weight compared to normal or constant light conditions.
Physiol Rep, 2019 • July 1, 2019
This study investigated the interactive effects of myostatin (Mstn) and AdipoRon on hepatic gene expression and function in a mouse hepatocyte line. Mstn increased fatty acid accumulation and desensit...
KEY FINDING: Myostatin (Mstn) increases fatty acid accumulation and desensitizes cellular responses to insulin in hepatocytes.
Trials, 2019 • September 5, 2019
This study investigates the effects of an 8-week low-carbohydrate/high-protein (LC/HP) dietary intervention on metabolic health, body composition, gut bacteria composition, and quality of life in indi...
KEY FINDING: The study aims to determine if a low-carbohydrate/high-protein diet improves glucose tolerance, insulin sensitivity, and β-cell function in individuals with SCI.
Trials, 2019 • January 1, 2019
This study protocol outlines a randomized controlled trial to investigate the acute effects of different upper-body exercise modalities on postprandial metabolic responses in men with spinal cord inju...
KEY FINDING: The study will compare the acute metabolic responses of persons with SCI to two novel, higher-intensity modes of upper-body exercise (CRT and HIIT) with a more traditional form of exercise (MICT) and rest (CON).
The Journal of Comparative Neurology, 2012 • February 8, 2012
This study aimed to evaluate the effects of post-SCI administration of 17b-estradiol on functional recovery and histopathology in a cervical model of SCI. The researchers found that post-SCI administr...
KEY FINDING: Post-SCI administration of 17b-estradiol decreased neuronal loss in the ventral horn, suggesting a neuroprotective effect.
Osteoporos Int, 2013 • March 1, 2013
This study assessed circulating proteins as biomarkers of bone status in men with chronic SCI, finding sclerostin significantly associated with bone mineral content and density at all sites tested. Th...
KEY FINDING: Lower sclerostin levels were significantly associated with lower bone mineral content and bone density at all skeletal sites tested.
Annals of Rehabilitation Medicine, 2013 • June 1, 2013
This study investigated the characteristics of abdominal obesity (AO) in community-dwelling individuals with spinal cord injury (SCI) compared to the general population (GP). It assessed factors such ...
KEY FINDING: The prevalence of abdominal obesity was similar in SCI persons (29.2%) and the general population (27.4%).
ASN NEURO, 2013 • August 7, 2013
This study demonstrates neuroendocrine signaling peptide alterations, associated with central inflammation and metabolic dysfunction post-SCI. The research provides evidence for the peripheral activat...
KEY FINDING: Chronic SCI results in decreased POMC and increased NPY expression in the hypothalamic ARC and PVN.