Browse the latest research summaries in the field of cardiovascular science for spinal cord injury patients and caregivers.
Showing 221-230 of 339 results
Medicine, 2019 • September 1, 2019
This network meta-analysis protocol outlines the methods for assessing the efficacy and safety of different doses of azilsartan medoxomil in patients with hypertension. The study will search multiple ...
KEY FINDING: This study will summarize all available data to provide reliable evidence of the value of different doses of azilsartan medoxomil for hypertension treatment.
The Journal of Spinal Cord Medicine, 2018 • July 1, 2018
This review describes the current state of cIMT acquisition and analysis quality in individuals with SCI. The primary finding of this review is that the current literature reporting cIMT values among ...
KEY FINDING: The study found that the overall reporting of quality methodology for cIMT in SCI literature was poor.
Nat Med, 2017 • June 1, 2017
This study demonstrates that pericytes play a major role in regulating capillary tone and blood flow in the spinal cord after SCI, leading to chronic hypoxia. The researchers found that AADC expressed...
KEY FINDING: SCI leads to chronic hypoxia in the spinal cord below the injury site due to excessive capillary tone.
Spinal Cord, 2008 • November 1, 2008
The purpose of this study was to examine the effects of FES-LCE training on systemic arterial compliance in persons with SCI. This investigation revealed for the first time that FES-LCE is effective i...
KEY FINDING: There was no significant change in large artery compliance after FES-LCE training.
JOURNAL OF NEUROTRAUMA, 2008 • December 1, 2008
This study evaluated the effect of active stand training on arterial blood pressure and heart rate and changes in response to orthostatic stress in individuals with SCI. Improvements in resting arteri...
KEY FINDING: Resting arterial blood pressure significantly increased in individuals with cervical SCI after 80 training sessions of stand LT.
Arch Phys Med Rehabil, 2009 • February 1, 2009
This systematic review examined the treatment of venous thromboembolism in SCI patients, finding good evidence for pharmacological prophylaxis. Research into non-pharmacological prophylaxis or treatm...
KEY FINDING: Low molecular weight heparin (LMWH) is more effective than unfractionated heparin (UFH) in preventing venous thromboembolic events and has a lower risk of bleeding complications.
Eur Spine J, 2009 • March 28, 2009
This case report describes a 47-year-old male who suffered a traumatic C7–D1 dislocation and experienced severe bradycardia with multiple episodes of cardiac arrest for two months post-injury. Despite...
KEY FINDING: A patient with a cervico-dorsal (C7-D1) spinal injury experienced persistent and recurrent cardiac arrests that did not resolve within the expected 4-6 weeks.
JOURNAL OF NEUROTRAUMA, 2009 • July 1, 2009
The study aimed to determine if initiating swim training acutely after spinal cord injury (SCI) is more beneficial than initiating it after 2 weeks. Rats with moderate to severe thoracic contusion SCI...
KEY FINDING: Acute swim training (initiated 3 days post-SCI) is less effective than training initiated at 2 weeks post-injury in improving swimming ability.
Arch Phys Med Rehabil, 2009 • May 1, 2009
This systematic review assessed the evidence for managing orthostatic hypotension (OH) in individuals with spinal cord injuries (SCI). The review identified 8 pharmacological and 21 non-pharmacologica...
KEY FINDING: Only one low-quality randomized controlled trial (RCT) supported the use of midodrine for OH management following SCI, providing Level 2 evidence.
Clin Auton Res, 2010 • February 1, 2010
This study investigated the cognitive function of individuals with SCI, comparing hypotensive and normotensive subjects over a 24-hour period. The findings suggest that chronic hypotension in SCI pati...
KEY FINDING: Memory was significantly impaired in the hypotensive group compared to the normotensive group (P<0.05).