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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Cardiovascular Science Research

Browse the latest research summaries in the field of cardiovascular science for spinal cord injury patients and caregivers.

Showing 91-100 of 339 results

Cardiovascular SciencePhysiologyRehabilitation

The effect of paired associative stimulation with a high-intensity cortical component and a high-frequency peripheral component on heart rate and heart rate variability in healthy subjects

Front. Rehabil. Sci., 2023 • July 26, 2023

This study evaluated the acute cardiovascular effects of a 20-min session of high PAS on 17 healthy individuals by measuring heart rate variability (HRV). The results showed a transient increase in pa...

KEY FINDING: A significant decrease in low-frequency (LF) power and low-frequency to high-frequency (HF) ratio was observed during stimulation, indicating increased parasympathetic activity.

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Spinal Cord InjuryCardiovascular ScienceResearch Methodology & Design

A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury: Recommendations on Hemodynamic Management

Global Spine Journal, 2024 • March 1, 2024

This guideline updates the 2013 AANS/CNS recommendations on hemodynamic management of patients with acute traumatic SCI, incorporating literature published since 2011. The guideline development group ...

KEY FINDING: The guideline suggests that MAP should be augmented to at least 75-80 mmHg as the “lower limit” in acute traumatic SCI patients.

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Spinal Cord InjuryCardiovascular ScienceBioinformatics

Cardiometabolic risk factor clustering in persons with spinal cord injury: A principal component analysis approach

The Journal of Spinal Cord Medicine, 2024 • January 1, 2024

This study used principal component analysis (PCA) to identify how cardiometabolic (CM) risk factors cluster in individuals with spinal cord injury (SCI) compared to non-SCI controls, revealing a six-...

KEY FINDING: Principal component analysis (PCA) identified six factor components (FC) explaining 77% and 82% of the total variance in the SCI and non-SCI cohorts, respectively.

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Spinal Cord InjuryCardiovascular ScienceNeurology

Protection of the Vascular System by Polyethylene Glycol Reduces Secondary Injury Following Spinal Cord Injury in Rats

Tissue Eng Regen Med, 2023 • September 12, 2023

This study investigates the neuroprotective effects of polyethylene glycol (PEG) on the vascular system following spinal cord injury (SCI) in rats. The results demonstrate that PEG reduces vascular pe...

KEY FINDING: PEG significantly reduced vascular permeability after SCI, indicating a protective effect on the blood-spinal cord barrier.

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Spinal Cord InjuryCardiovascular ScienceRehabilitation

Incidence and risk factors of deep vein thrombosis and pulmonary thromboembolism after spinal cord disease at a rehabilitation unit: a retrospective study

J Yeungnam Med Sci, 2023 • September 20, 2023

This retrospective study investigated the incidence and risk factors of deep vein thrombosis (DVT) and pulmonary thromboembolism (PTE) in 271 Korean patients with spinal cord disease admitted to a reh...

KEY FINDING: The incidence of DVT and PTE in patients with spinal cord disease was 6.3% and 6.3%, respectively, within 3 months of disease onset.

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Spinal Cord InjuryCardiovascular ScienceNeurology

Effects of two different paradigms of electrical stimulation exercise on cardio-metabolic risk factors after spinal cord injury. A randomized clinical trial

Frontiers in Neurology, 2023 • September 22, 2023

The addition of 12 weeks of FES-LEC following 12 weeks of NMES-RT did not result in additional increase in muscle size. NMES-RT managed to increase leg VO2 peak compared to PMT; however, the addition ...

KEY FINDING: NMES-RT + FES group showed a trend of a greater VO2 peak in P1 compared to PMT + FES.

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Spinal Cord InjuryCardiovascular ScienceNeurology

Differentiating essential hypertension from autonomic dysreflexia: a case report

Spinal Cord Series and Cases, 2023 • October 16, 2023

This case report highlights the challenge of differentiating essential hypertension from autonomic dysreflexia in a patient with a C1 spinal cord injury. The patient's case required extensive investig...

KEY FINDING: Essential hypertension can occur in patients with spinal cord injury, even those expected to have low blood pressure.

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Spinal Cord InjuryCardiovascular ScienceNeurology

Treatment of postprandial hypotension with acarbose in an adult with cervical spinal cord injury: a case report

Spinal Cord Series and Cases, 2023 • December 1, 2023

This case report describes the successful treatment of postprandial hypotension (PPH) with acarbose in a 26-year-old male with a complete cervical spinal cord injury (SCI). The patient presented with ...

KEY FINDING: Low-dose acarbose (25mg three times daily with meals) effectively resolved postprandial hypotension symptoms in a young, non-diabetic adult with cervical SCI.

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Cardiovascular ScienceNeurologyRehabilitation

Reliability of five-minute vs. one-hour heart rate variability metrics in individuals with spinal cord injury

PeerJ, 2023 • December 18, 2023

The study investigated test-retest reliability of HRV metrics in individuals with SCI using a 1-h measurement in a supine position, comparing it with a 5-min measurement. Relative reliability was gene...

KEY FINDING: Relative reliability was higher for the 1-h than for the 5-min duration in the overall SCI group for all HRV metrics.

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Spinal Cord InjuryCardiovascular ScienceHealthcare

Developing and Evaluating Data Infrastructure and Implementation Tools to Support Cardiometabolic Disease Indicator Data Collection

Top Spinal Cord Inj Rehabil, 2023 • January 1, 2023

This quality improvement (QI) project aimed to develop data infrastructure and implementation tools to support the collection of cardiometabolic disease (CMD) indicator data among individuals with spi...

KEY FINDING: An AI tool was effective for extracting data with a low error rate (<2%).

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