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  4. Incidence and risk factors of deep vein thrombosis and pulmonary thromboembolism after spinal cord disease at a rehabilitation unit: a retrospective study

Incidence and risk factors of deep vein thrombosis and pulmonary thromboembolism after spinal cord disease at a rehabilitation unit: a retrospective study

J Yeungnam Med Sci, 2023 · DOI: 10.12701/jyms.2023.00689 · Published: September 20, 2023

Spinal Cord InjuryCardiovascular ScienceRehabilitation

Simple Explanation

This study examines the occurrence of deep vein thrombosis (DVT) and pulmonary thromboembolism (PTE) in Korean patients with spinal cord disease undergoing rehabilitation. These conditions are major complications that can arise due to impaired mobility and changes in blood coagulation following spinal cord injuries. The study found that both DVT and PTE occurred in 6.3% of the patients within three months of the spinal cord disease onset. Older age (65 years or older) and limited ability to walk independently were identified as risk factors for developing DVT. The researchers suggest that early screening for DVT and PTE should be conducted in patients with acute-to-subacute spinal cord disease, regardless of whether they exhibit specific risk factors, to ensure timely intervention and prevention of severe complications.

Study Duration
January 2012 and January 2022
Participants
271 patients with spinal cord disease
Evidence Level
Not specified

Key Findings

  • 1
    The incidence of DVT and PTE in patients with spinal cord disease was 6.3% and 6.3%, respectively, within 3 months of disease onset.
  • 2
    Age of ≥65 years and a low Functional Ambulation Category (FAC) score (≤1) were identified as independent risk factors for DVT development.
  • 3
    A traumatic cause of injury and the presence of DVT were significant independent risk factors for PTE.

Research Summary

This retrospective study investigated the incidence and risk factors of deep vein thrombosis (DVT) and pulmonary thromboembolism (PTE) in 271 Korean patients with spinal cord disease admitted to a rehabilitation unit within 3 months of disease onset. The study found that the incidences of DVT and PTE were both 6.3%. Risk factor analysis revealed that age ≥65 years and a low Functional Ambulation Category (FAC) score (≤1) were significantly associated with DVT development, while traumatic cause of injury and DVT were significant risk factors for PTE. The conclusion emphasizes the importance of early screening for DVT and PTE in patients with acute-to-subacute spinal cord disease, irrespective of the presence or absence of specific risk factors, to ensure timely intervention and prevention of complications.

Practical Implications

Early Screening Protocols

Hospitals and rehabilitation centers should implement routine screening protocols for DVT and PTE in patients with spinal cord disease, especially those admitted within 3 months of onset.

Targeted Interventions

Interventions should target modifiable risk factors, such as improving functional ambulation through rehabilitation programs, and providing prophylactic measures for high-risk patients (e.g., those aged ≥65 years).

Increased Awareness

Healthcare providers should be educated about the heightened risk of DVT and PTE in spinal cord disease patients, particularly those with traumatic injuries, to promote early detection and management.

Study Limitations

  • 1
    Retrospective study design
  • 2
    Assessments of DVT and PTE were not performed routinely
  • 3
    Diagnostic methods for DVT varied

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